PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26901413-11	2016	Likewise, isolated CD4+ T cells under ArtinM stimulus augmented the expression of TGF-beta mRNA and released high levels of IL-17.	artinm	38-44	interleukin 17A	Mus musculus	124-129	
30216978-0	2018	The Response of IL-17-Producing B Cells to ArtinM Is Independent of Its Interaction with TLR2 and CD14.	artinm	43-49	interleukin 17A	Mus musculus	16-21	
30216978-3	2018	Here, we further investigated the effects of ArtinM on the production of IL-17 by B cell activation.	artinm	45-51	interleukin 17A	Mus musculus	73-78	
30216978-4	2018	We showed that ArtinM activates murine B cells, increasing IL-17 and IL-12p40 production.	artinm	15-21	interleukin 17A	Mus musculus	59-64	
30216978-5	2018	The direct effect of ArtinM was sufficient to induce IL-17 production in B cells, and we did not find differences in the levels of IL-17 between the B cells purified from the wild-type (WT) and knockout (KO) mice for TLR2 or CD14 in the presence of ArtinM.	artinm	21-27	interleukin 17A	Mus musculus	53-58	
27222857-2	2016	(2016) [2] that ArtinM induces the IL-17 production through interaction with CD4(+) T cells and stimulation of IL-23 and IL-1.	artinm	16-22	interleukin 17A	Mus musculus	35-40	
26901413-0	2016	IL-17 Induction by ArtinM is Due to Stimulation of IL-23 and IL-1 Release and/or Interaction with CD3 in CD4+ T Cells.	artinm	19-25	interleukin 17A	Mus musculus	0-5	
26901413-3	2016	In the murine model of Candida albicans infection, it was verified that, in addition to Th1, ArtinM induces Th17 immunity manifested by high IL-17 levels in the treated animals.	artinm	93-99	interleukin 17A	Mus musculus	141-146	
26901413-4	2016	Herein, we investigated the mechanisms accounting for the ArtinM-induced IL-17 production.	artinm	58-64	interleukin 17A	Mus musculus	73-78	
26901413-5	2016	We found that ArtinM stimulates the IL-17 production by spleen cells in BALB/c or C57BL/6 mice, a response that was significantly reduced in the absence of IL-23, MyD88, or IL-1R.	artinm	14-20	interleukin 17A	Mus musculus	36-41	
26901413-7	2016	Consistently, in cell suspensions depleted of macrophages, the IL-17 production stimulated by ArtinM was reduced by 53% and the exogenous IL-23 acted synergistically with ArtinM in promoting IL-17 production by spleen cell suspensions.	artinm	94-100	interleukin 17A	Mus musculus	63-68	
26901413-7	2016	Consistently, in cell suspensions depleted of macrophages, the IL-17 production stimulated by ArtinM was reduced by 53% and the exogenous IL-23 acted synergistically with ArtinM in promoting IL-17 production by spleen cell suspensions.	artinm	171-177	interleukin 17A	Mus musculus	191-196	
26901413-9	2016	Therefore, we investigated whether ArtinM exerts a direct effect on CD4+ T cells in promoting IL-17 production.	artinm	35-41	interleukin 17A	Mus musculus	94-99	
26901413-13	2016	We verified that ArtinM increased the IL-17 production significantly, a response that was inhibited when the CD4+ T cells were pre-incubated with anti-CD3 antibody.	artinm	17-23	interleukin 17A	Mus musculus	38-43	
26901413-14	2016	In conclusion, ArtinM stimulates the production of IL-17 by CD4+ T cells in two major ways: (I) through the induction of IL-23 and IL-1 by APCs and (II) through the direct interaction with CD3 on the CD4+ T cells.	artinm	15-21	interleukin 17A	Mus musculus	51-56