PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12515820-4 2003 In this setting, CTLA-4 regulated the accumulation/retention of TCRzeta in the signaling complex, as the lipid raft fractions from CTLA-4KO T cells contained significantly higher amounts of the TCR components when compared with wild-type littermates. tcrzeta 64-71 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 17-23 12515820-4 2003 In this setting, CTLA-4 regulated the accumulation/retention of TCRzeta in the signaling complex, as the lipid raft fractions from CTLA-4KO T cells contained significantly higher amounts of the TCR components when compared with wild-type littermates. tcrzeta 64-71 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 131-137 12515820-5 2003 In contrast, coligation of CTLA-4 with the TCR during T cell activation selectively decreased the amount of TCRzeta that accumulated in the rafts. tcrzeta 108-115 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 27-33 11449357-3 2001 In contrast, in this study, we demonstrate that, although not essential, the YVKM motif contributes to optimal CTLA-4 blockage of TCRzeta or combined TCRzeta/CD28 signaling. tcrzeta 130-137 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 111-117 11449357-3 2001 In contrast, in this study, we demonstrate that, although not essential, the YVKM motif contributes to optimal CTLA-4 blockage of TCRzeta or combined TCRzeta/CD28 signaling. tcrzeta 150-157 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 111-117 9856951-2 1998 The association of TCRzeta with CTLA-4, reconstituted in 293 transfectants, was enhanced by p56(lck)-induced tyrosine phosphorylation. tcrzeta 19-26 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 32-38 9856951-3 1998 Coexpression of the CTLA-4-associated tyrosine phosphatase, SHP-2, resulted in dephosphorylation of TCRzeta bound to CTLA-4 and abolished the p56(lck)-inducible TCRzeta-CTLA-4 interaction. tcrzeta 100-107 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 20-26 9856951-3 1998 Coexpression of the CTLA-4-associated tyrosine phosphatase, SHP-2, resulted in dephosphorylation of TCRzeta bound to CTLA-4 and abolished the p56(lck)-inducible TCRzeta-CTLA-4 interaction. tcrzeta 100-107 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 117-123 9856951-3 1998 Coexpression of the CTLA-4-associated tyrosine phosphatase, SHP-2, resulted in dephosphorylation of TCRzeta bound to CTLA-4 and abolished the p56(lck)-inducible TCRzeta-CTLA-4 interaction. tcrzeta 100-107 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 117-123 9856951-4 1998 Thus, CTLA-4 inhibits TCR signal transduction by binding to TCRzeta and inhibiting tyrosine phosphorylation after T cell activation. tcrzeta 60-67 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 6-12