PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7619077-2	1995	In recombinant rat liver PFK-2/FBPase-2, mutation of Arg-225 to Ser increased the Km of PFK-2 for fructose-6-phosphate (Fru-6-P) 7-fold at pH 6 and decreased PFK-2 activity at suboptimal substrate concentrations between pH 6 and 9.5.	fructose-6-phosphate	98-118	fructose-bisphosphatase 2	Rattus norvegicus	31-39	
29507044-2	2018	Gluconeogenesis requires FBP2, a muscle-specific form of fructose bisphosphatase that converts fructose-1,6-bisphosphate (F-1,6-bisP) to fructose-6-phosphate (F-6-P) opposing the activity of the ATP-consuming enzyme phosphofructokinase (PFK).	fructose-6-phosphate	137-157	fructose-bisphosphatase 2	Rattus norvegicus	25-29	
29507044-2	2018	Gluconeogenesis requires FBP2, a muscle-specific form of fructose bisphosphatase that converts fructose-1,6-bisphosphate (F-1,6-bisP) to fructose-6-phosphate (F-6-P) opposing the activity of the ATP-consuming enzyme phosphofructokinase (PFK).	fructose-6-phosphate	159-164	fructose-bisphosphatase 2	Rattus norvegicus	25-29	
29507044-4	2018	In an attempt to increase substrate cycling between F-6-P and F-1,6-bisP and alter glucose metabolism, we overexpressed FBP2 using a muscle-specific adeno-associated virus (AAV-tMCK-FBP2).	fructose-6-phosphate	52-57	fructose-bisphosphatase 2	Rattus norvegicus	120-124	
19014931-7	2008	Consistent with the inhibition of FBPase, glucose-lowering was associated with an accumulation of hepatic d-fructose 1,6-bisphosphate and a reduction in hepatic d-fructose 6-phosphate.	fructose-6-phosphate	161-183	fructose-bisphosphatase 2	Rattus norvegicus	34-40	
11023824-1	2000	Fructose-1,6-bisphosphatase (FBPase; EC 3.1.3.11), an important gluconeogenic enzyme, catalyses the hydrolysis of fructose 1, 6-bisphosphate to fructose 6-phosphate and P(i).	fructose-6-phosphate	144-164	fructose-bisphosphatase 2	Rattus norvegicus	29-35	
7619077-2	1995	In recombinant rat liver PFK-2/FBPase-2, mutation of Arg-225 to Ser increased the Km of PFK-2 for fructose-6-phosphate (Fru-6-P) 7-fold at pH 6 and decreased PFK-2 activity at suboptimal substrate concentrations between pH 6 and 9.5.	fructose-6-phosphate	120-127	fructose-bisphosphatase 2	Rattus norvegicus	31-39	
7619077-9	1995	In recombinant rat muscle PFK-2/FBPase-2, mutation of Arg-104 to Ser increased the Km for Fru-6-P 60-fold, increased the IC50 of citrate, increased the Vmax.	fructose-6-phosphate	90-97	fructose-bisphosphatase 2	Rattus norvegicus	32-40	
7619077-13	1995	of FBPase-2 3-fold, increased the Km for Fru-2,6-P2 70-fold and increased the IC50 of Fru-6-P at least 300-fold.	fructose-6-phosphate	86-93	fructose-bisphosphatase 2	Rattus norvegicus	3-11