PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12611640-4	2002	We report that dantrolene, a specific ryanodine receptor antagonist, was able to significantly reduce the apoptotic cell death in CGC cultures and in hyppocampal CA1 and parietal cortex regions.	Dantrolene	15-25	carbonic anhydrase 1	Rattus norvegicus	162-165	
7699830-0	1995	[Effects of dantrolene on histological and behavioral outcome in rat CA1 hippocampus after global transient cerebral ischemia].	Dantrolene	12-22	carbonic anhydrase 1	Rattus norvegicus	69-72	
11719138-0	2001	Dantrolene ameliorates delayed cell death and concomitant DNA fragmentation in the rat hippocampal CA1 neurons subjected to mild ischemia.	Dantrolene	0-10	carbonic anhydrase 1	Rattus norvegicus	99-102	
8773402-1	1996	In intracellular recordings by current clamp, dantrolene (sodium salt, 20 microM) regularly depolarized CA1 neurons (by approximately 13 mV), even in the presence of tetrodotoxin.	Dantrolene	46-56	carbonic anhydrase 1	Rattus norvegicus	104-107	
7602615-8	1995	The group treated with Dantrolene showed no neuropathological changes in the hippocampal CA3 region and only slight changes in the Ca1 region, while the neuron loss in the Nimodipine group did not differ from that of its control group.	Dantrolene	23-33	carbonic anhydrase 1	Rattus norvegicus	131-134	
11873048-0	2002	Effects of dantrolene on extracellular glutamate concentration and neuronal death in the rat hippocampal CA1 region subjected to transient ischemia.	Dantrolene	11-21	carbonic anhydrase 1	Rattus norvegicus	105-108	
11873048-9	2002	The number of intact hippocampal CA1 neurons (mean +/- SD; cells/mm) in dantrolene-treated rats (78 +/- 21) was significantly higher than that in artificial cerebrospinal fluid- (35 +/- 14; P < 0.001) and dimethyl sulfoxide-treated (56 +/- 11; P < 0.05) animals.	Dantrolene	72-82	carbonic anhydrase 1	Rattus norvegicus	33-36	
11873048-11	2002	CONCLUSIONS: Intracerebroventricular dantrolene prevents delayed neuronal loss in the rat hippocampal CA1 region subjected to transient ischemia; however, this neuroprotection cannot be accounted for only by the reduced concentrations of extracellular glutamate during ischemia.	Dantrolene	37-47	carbonic anhydrase 1	Rattus norvegicus	102-105	
9914278-1	1999	Temporary replacement of glucose by 2-deoxyglucose (2-DG; but not sucrose) is followed by long-term potentiation of CA1 synaptic transmission (2-DG LTP), which is Ca2+-dependent and is prevented by dantrolene or N-methyl--aspartate (NMDA) antagonists.	Dantrolene	198-208	carbonic anhydrase 1	Rattus norvegicus	116-119	
7699830-6	1995	Thus we postulated that dantrolene might improve neuronal survival in vulnerable regions to ischemia such as the CA1 hippocampus.	Dantrolene	24-34	carbonic anhydrase 1	Rattus norvegicus	113-116	
31987836-13	2020	Notably, dantrolene promoted neuroprotective effects by decreasing neuronal cell loss in CA1 and CA3, which explains the increased levels of synaptic proteins, and the apparent lack of positive effect on pathological plasticity.	Dantrolene	9-19	carbonic anhydrase 1	Rattus norvegicus	89-92	
2710411-5	1989	We now report that pharmacological blockade of intraneuronal calcium release with 20 microM dantrolene-sodium (dantrium) completely blocks the induction of LTP in the CA1 region of the rat hippocampal slice.	Dantrolene	92-109	carbonic anhydrase 1	Rattus norvegicus	167-170	
2710411-5	1989	We now report that pharmacological blockade of intraneuronal calcium release with 20 microM dantrolene-sodium (dantrium) completely blocks the induction of LTP in the CA1 region of the rat hippocampal slice.	Dantrolene	111-119	carbonic anhydrase 1	Rattus norvegicus	167-170