PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31696059-11 2019 For patients with BBM receiving sequential therapy beyond the first disease progression after crizotinib treatment (1st PD), crizotinib beyond progressive disease (CBPD) plus local therapy can lead to a significantly longer PFS2 (67.0 vs. 21.0 weeks; p = 0.046). crizotinib 125-135 GINS complex subunit 2 Homo sapiens 224-228