PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28388666-9 2017 CONCLUSIONS: Picroside II could protect the nervous system possibly through reducing the content of ROS by down-regulating the expression of Rac-1 and Nox2 and could protect the BBB through reducing the expression of ROCK, MLCK, and MMP-2, while enhancing the expression of claudin-5. picroside II 13-25 matrix metallopeptidase 2 Homo sapiens 233-238