PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23121773-6 2013 The oral antidiabetic drugs glibenclamide, glimepiride and nateglinide inhibited the transport of the model substrate bromosulfophthalein, particularly the OATP2B1-mediated uptake. Glyburide 28-41 solute carrier organic anion transporter family member 2B1 Homo sapiens 156-163 24839071-2 2014 Comprehensive in vitro studies suggested that glyburide is a highly permeable drug with substrate affinity to multiple efflux pumps and to organic anion transporting polypeptide (OATP)1B1 and OATP2B1. Glyburide 46-55 solute carrier organic anion transporter family member 2B1 Homo sapiens 192-199 23121773-8 2013 For glibenclamide, inhibitory constants (Ki values) of 13.6 muM, 8.1 muM and 0.5 muM for OATP1B1-, OATP1B3- and OATP2B1-mediated BSP uptake were determined. Glyburide 4-17 solute carrier organic anion transporter family member 2B1 Homo sapiens 112-119 32483763-8 2020 The OATP2B1 inhibitors, including atorvastatin, bromosulfophthalein, glibenclamide, sulfasalazine, talinolol, and estrone 3-sulfate, inhibited the DBF and the 5-CF transport. Glyburide 69-82 solute carrier organic anion transporter family member 2B1 Homo sapiens 4-11 15640378-8 2005 Glibenclamide, a hypoglycemic drug, was identified for the first time as a substrate for OATP-B with a K(t) value of 6.26 microM. Glyburide 0-13 solute carrier organic anion transporter family member 2B1 Homo sapiens 89-95 15640378-9 2005 GFJ and OJ inhibited the OATP-B-mediated uptake of glibenclamide. Glyburide 51-64 solute carrier organic anion transporter family member 2B1 Homo sapiens 25-31 15640378-10 2005 These results suggest that citrus juices may inhibit the intestinal absorption of anionic drugs, such as glibenclamide, via the inhibition of OATP-B. Glyburide 105-118 solute carrier organic anion transporter family member 2B1 Homo sapiens 142-148 17178262-8 2006 Furthermore, estrone-3-sulfate transport into OATP2B1-overexpressing Madin-Darby canine kidney II cells was inhibited by various drugs, including atorvastatin, simvastatin, cerivastatin, glyburide (INN, glibenclamide), and gemfibrozil, with the most pronounced effect being found for atorvastatin (inhibition constant, 0.7 +/- 0.4 micromol/L). Glyburide 187-196 solute carrier organic anion transporter family member 2B1 Homo sapiens 46-53 17178262-8 2006 Furthermore, estrone-3-sulfate transport into OATP2B1-overexpressing Madin-Darby canine kidney II cells was inhibited by various drugs, including atorvastatin, simvastatin, cerivastatin, glyburide (INN, glibenclamide), and gemfibrozil, with the most pronounced effect being found for atorvastatin (inhibition constant, 0.7 +/- 0.4 micromol/L). Glyburide 203-216 solute carrier organic anion transporter family member 2B1 Homo sapiens 46-53 30652318-5 2019 In contrast, atorvastatin, bosentan, etoposide, fexofenadine, fluvastatin, glibenclamide and simeprevir were broadly transported by recombinant monkey OATP1B1, OATP1B3 and OATP2B1. Glyburide 75-88 solute carrier organic anion transporter family member 2B1 Homo sapiens 172-179