PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24657787-7	2014	Conversely, another caspase 1 inhibitor, glyburide, significantly inhibited virus infection suggesting it had off-target effects on related enzymes or interfered with infection via non-enzymatic mechanisms.	Glyburide	41-50	caspase 1	Homo sapiens	20-29	
26435646-10	2015	Glyburide inhibited urate-induced caspase-1 activation, IL-1beta secretion and proliferation.	Glyburide	0-9	caspase 1	Homo sapiens	34-43	
29432801-8	2018	The inhibition assay showed that glybenclamide (a K+ efflux inhibitor that blocks NLRP3 inflammasome activation) and N-benzyloxycarbony-Val-Ala-Asp (O-methyl)-fluoromethylketone (Z-VAD-FMK; a caspase-1 inhibitor) and NLRP3 depletion with siRNAs reduced the levels of IL-1beta and IL-18 release.	Glyburide	33-46	caspase 1	Homo sapiens	192-201	
24285499-8	2014	Glyburide completely blocked CP-induced activation of caspase-1 and the production of IL-1beta at 4 h. At 24 h, glyburide reduced two markers of inflammation by 30-50% and reversed much of the inflammatory morphology.	Glyburide	0-9	caspase 1	Homo sapiens	54-63	
10601248-5	1999	Two inhibitors of anion transport, glyburide and ethacrynic acid, blocked maturation of both caspase-1 and pro-IL-1beta and prevented release of the propolypeptides.	Glyburide	35-44	caspase 1	Homo sapiens	93-102	
35221708-5	2022	The applicability and effectiveness of the CASPorter cell line were tested by co-treatment with Dox and four known CASP1/NLRP3 inhibitors (MCC950, Glyburide, VX-765 and VRT-043198).	Glyburide	147-156	caspase 1	Homo sapiens	115-120	
29056256-8	2017	These findings suggest that trophoblasts can secrete IL-1beta through the NLRP3/caspase-1 pathway, which is suppressed by glibenclamide, and that the TLR4-mediated NLRP3 inflammasome pathway is more likely to be stimulated in undifferentiated than differentiated trophoblasts.	Glyburide	122-135	caspase 1	Homo sapiens	80-89