PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28266648-3 2017 Here, we show that raffinose, a ubiquitously present trisaccharide in plants, activated the transcriptional activity of LXRalpha/beta, which led to the induction of genes required for keratinocyte differentiation such as involucrin and filaggrin, and genes involved in lipid metabolism and transport including SCD1 and ABCA1 in both HaCaT and normal human epidermal keratinocytes. Raffinose 19-28 stearoyl-CoA desaturase Homo sapiens 310-314