PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17436566-2 2007 The relationship between experimentally derived data on the antioxidant capacity, cytotoxicity and COX-2 inhibition for a range of 2-methoxyphenols and their calculated descriptors was investigated. Guaiacol 131-147 mitochondrially encoded cytochrome c oxidase II Homo sapiens 99-104 17436566-3 2007 MATERIALS AND METHODS: Quantitative structure-activity relationship (QSAR) studies were performed on a series of 2-methoxyphenols that act as COX-2 inhibitors using electronic descriptors, such as the highest occupied molecular orbital (HOMO), the lowest unoccupied molecular orbital (LUMO), ionization potential (IP), chemical hardness (q), and electronegativity (chi), which were calculated by the CONFLEXIPM3 method. Guaiacol 113-129 mitochondrially encoded cytochrome c oxidase II Homo sapiens 142-147 17436566-8 2007 The majority of 2-methoxyphenols studied were COX-2 inhibitors. Guaiacol 16-32 mitochondrially encoded cytochrome c oxidase II Homo sapiens 46-51