PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9498789-6 1998 Treatment of infected mice with rIL-12 to reverse the Th2 polarity of the parasite-specific immune response restores tolerance of both Th1 and Th2 responses to OVA. ril-12 32-38 heart and neural crest derivatives expressed 2 Mus musculus 54-57 14500667-2 2003 When exogenous rIL-12 was administered to T. spiralis-infected NIH mice, this resulted in significant suppression of intestinal mast cell responses, delayed worm expulsion, increased muscle larvae burdens, and a transient, but significant decrease in early Th2 cytokine secretion. ril-12 15-21 heart and neural crest derivatives expressed 2 Mus musculus 257-260 10706693-5 2000 Nevertheless, while addition of exogenous rIL-12 resulted in transitory IFN-gamma production by Th2 lymphocytes from both wild-type and Stat6-deficient mice, IL-4 synthesis was preserved in the former, but temporarily ablated in the latter cells. ril-12 42-48 heart and neural crest derivatives expressed 2 Mus musculus 96-99 11527435-8 2001 Specific proliferation of T cells to cryptosporidial antigen and Th1 and Th2 mRNA cytokine expression was markedly decreased in rIL-12-treated mice. ril-12 128-134 heart and neural crest derivatives expressed 2 Mus musculus 73-76 9498789-6 1998 Treatment of infected mice with rIL-12 to reverse the Th2 polarity of the parasite-specific immune response restores tolerance of both Th1 and Th2 responses to OVA. ril-12 32-38 heart and neural crest derivatives expressed 2 Mus musculus 143-146 24840346-0 2014 Serine protease inhibition attenuates rIL-12-induced GZMA activity and proinflammatory events by modulating the Th2 profile from estrogen-treated mice. ril-12 38-44 heart and neural crest derivatives expressed 2 Mus musculus 112-115