PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14707132-6	2004	Of potential regulators surveyed, endogenous OSR1 is activated only by osmotic stresses, notably sorbitol and to a lesser extent NaCl.	Sorbitol	97-105	oxidative stress responsive kinase 1	Homo sapiens	45-49	
24191005-4	2013	Inhibition of the PI3K target pathway, the mammalian target of rapamycin complex 2 (mTORC2), by depletion of Sin1, one of its components, decreased activation of OSR1 by sorbitol and reduced activity of the OSR1 substrate, the sodium, potassium, two chloride cotransporter, in HeLa cells.	Sorbitol	170-178	oxidative stress responsive kinase 1	Homo sapiens	162-166	
22989884-8	2012	C-terminal fragments of WNK1 that contain three RFXV interaction motifs can bind OSR1, block activation of OSR1 by sorbitol, and prevent the OSR1-induced enhancement of ion co-transporter activity in cells, further supporting the conclusion that association with WNK1 is required for OSR1 activation and function at least in some contexts.	Sorbitol	115-123	oxidative stress responsive kinase 1	Homo sapiens	107-111	
22989884-8	2012	C-terminal fragments of WNK1 that contain three RFXV interaction motifs can bind OSR1, block activation of OSR1 by sorbitol, and prevent the OSR1-induced enhancement of ion co-transporter activity in cells, further supporting the conclusion that association with WNK1 is required for OSR1 activation and function at least in some contexts.	Sorbitol	115-123	oxidative stress responsive kinase 1	Homo sapiens	107-111	
22989884-8	2012	C-terminal fragments of WNK1 that contain three RFXV interaction motifs can bind OSR1, block activation of OSR1 by sorbitol, and prevent the OSR1-induced enhancement of ion co-transporter activity in cells, further supporting the conclusion that association with WNK1 is required for OSR1 activation and function at least in some contexts.	Sorbitol	115-123	oxidative stress responsive kinase 1	Homo sapiens	107-111