PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10818227-6	2000	Further dissection of caspase involvement in RIP3-induced apoptosis indicated inhibition by the more specific inhibitors Z-DEVD (caspase-3, -6, -7, -8, and -10) and Z-VDVAD (caspase-2).	z-devd	121-127	caspase 3	Homo sapiens	129-172	
18700866-8	2008	In addition, CPT-induced cell death was reversed by pre-treatment with z-DEVD, a caspase-3-specific inhibitor.	z-devd	71-77	caspase 3	Homo sapiens	81-90	
14656672-6	2004	The non-selective caspase inhibitor Z-VAD, the caspase-3 selective inhibitor Z-DEVD, and the growth factor insulin like growth factor (IGF)-1 inhibited chondrocyte apoptosis induced by collagenase treatment.	z-devd	77-83	caspase 3	Homo sapiens	47-56	
22607681-2	2012	As proof of concept, we designed and synthesized probes for caspase-3 activity (Z-DEVD-SiR600) and leucine aminopeptidase activity (Leu-SiR600).	z-devd	80-86	caspase 3	Homo sapiens	60-69	
22607681-3	2012	Caspase-3-mediated cleavage of Z-DEVD-SiR600 resulted in a large bathochromic shift (93 nm) of the absorption maximum and a 432-fold fluorescence enhancement.	z-devd	31-37	caspase 3	Homo sapiens	0-9	
12567892-8	2002	The caspase-3 activity increased markedly after treatment with DADAG for 24 h. The apoptotic signals were suppressed by z-VAD.fmk (a general inhibitor of caspases), whereas z-DEVD.fmk, a selective inhibitor of caspase-3, only induced partial reversion of the apoptotic effects.	z-devd	173-179	caspase 3	Homo sapiens	4-13	
12567892-8	2002	The caspase-3 activity increased markedly after treatment with DADAG for 24 h. The apoptotic signals were suppressed by z-VAD.fmk (a general inhibitor of caspases), whereas z-DEVD.fmk, a selective inhibitor of caspase-3, only induced partial reversion of the apoptotic effects.	z-devd	173-179	caspase 3	Homo sapiens	210-219	
10733772-6	2000	Caspase-3 activity, assayed by Z-DEVD cleavage, increased from 20% to 215% (P <.05).	z-devd	31-37	caspase 3	Homo sapiens	0-9	
34666646-10	2022	z-DEVD, a specific inhibitor of caspase-3, reduced lobaplatin-mediated GSDME cleavage and concurrently inhibited pyroptosis.	z-devd	0-6	caspase 3	Homo sapiens	32-41	
34808347-6	2022	Furthermore, promoting cellular antiapoptotic state via the knockdown of Bax with siRNA and FADD with antisense mRNA or the treatment with the Caspase-3 inhibitor, Z-DEVD, also raised viral DNA.	z-devd	164-170	caspase 3	Homo sapiens	143-152	
29956787-8	2018	All the tested caspase inhibitors (Z-VAD for pan-caspases, Z-DEVD for caspase-3, Z-IETD for caspase-8 and Z-LEHD for caspase-9) decreased the percentages of sub-G1 and Annexin V-FITC-stained cells in the H2O2-treated Calu-6 and A549 cells.	z-devd	59-65	caspase 3	Homo sapiens	70-79	
29983883-5	2018	Exposure of cells to Z-DEVD, an inhibitor of caspase-3 markedly reduced the thymoquinone-induced down-regulation of UHRF1, while proteosomal inhibitor MG132 had no such effect.	z-devd	21-27	caspase 3	Homo sapiens	45-54