PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27626217-5	2016	A total of 48 patients (48/81, 59.3%) were found to have DNMT3A mutations upon achieving CR.	Chromium	89-91	DNA methyltransferase 3 alpha	Homo sapiens	57-63	
26759106-8	2015	DNMT3A+/FLT3-ITD+ CN-AML patients(n=14)had higher ORR and CR rates than DNMT3A-/FLT3-ITD+CN- AML patients(n=15)(P= 0.040 and 0.042, respectively).	Chromium	58-60	DNA methyltransferase 3 alpha	Homo sapiens	0-6	
26759106-13	2015	Compared to DNMT3A-/FLT3- ITD+ CN- AML patients, DNMT3A+/ FLT3-ITD+ CN-AML patients had higher ORR and CR rates.	Chromium	103-105	DNA methyltransferase 3 alpha	Homo sapiens	49-55	
24844834-6	2014	After treated by Cr (VI) for 24 h, the expression of mRNA and protein level among DNMT1, DNMT3a, DNMT3b and MBD2 decreased significantly in healthy 16HBE cells; and the expression of DNMT1 and DNMT3a decreased in PARG deficiency cells.	Chromium	17-19	DNA methyltransferase 3 alpha	Homo sapiens	89-95	
24844834-6	2014	After treated by Cr (VI) for 24 h, the expression of mRNA and protein level among DNMT1, DNMT3a, DNMT3b and MBD2 decreased significantly in healthy 16HBE cells; and the expression of DNMT1 and DNMT3a decreased in PARG deficiency cells.	Chromium	17-19	DNA methyltransferase 3 alpha	Homo sapiens	193-199	
21967546-8	2012	OS was not affected by DNMT3A mutation (P = 0.251), but OS of patients who reached CR was longer in DNMT3A negative cases (P = 0.025).	Chromium	83-85	DNA methyltransferase 3 alpha	Homo sapiens	100-106	
21670448-7	2011	In cytogenetically normal (CN) AML, 27.2% harbored DNMT3A mutations that independently predicted shorter OS (HR = 2.46; 95% CI, 1.58 to 3.83; P < .001) and lower CR rate (OR, 0.42; 95% CI, 0.21 to 0.84; P = .015), but not RFS (P = .32).	Chromium	165-167	DNA methyltransferase 3 alpha	Homo sapiens	51-57	
21670448-8	2011	Within patients with CN-AML, DNMT3A mutations had an unfavorable effect on OS, RFS, and CR rate in NPM1/FLT3-ITD high-risk but not in low-risk patients.	Chromium	88-90	DNA methyltransferase 3 alpha	Homo sapiens	29-35