PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15328100-11	2004	The suppression of IL-12(p70) and TNF-alpha in maturing DCs may explain the reduction in hepatic inflammation observed during ribavirin monotherapy.	Ribavirin	126-135	tumor necrosis factor	Homo sapiens	34-43	
23300158-5	2013	This report also shows, for the first time, that the deleterious over-stimulation by TNF-alpha is mediated by nuclear factor-kappaB, and describes the effect of ribavirin on cytokine production following ANDV infection.	Ribavirin	161-170	tumor necrosis factor	Homo sapiens	85-94	
15328100-8	2004	In contrast, ribavirin at physiological doses had no effect on DC maturation but markedly suppressed the production of TNF-alpha, IL-10, and IL-12(p70).	Ribavirin	13-22	tumor necrosis factor	Homo sapiens	119-128	
25131720-0	2015	The role of IL-28, IFN-gamma, and TNF-alpha in predicting response to pegylated interferon/ribavirin in chronic HCV patients.	Ribavirin	91-100	tumor necrosis factor	Homo sapiens	34-43	
18333370-3	2007	The adipokines-leptin, adiponectin, TNF-alpha-, which are modified in obesity, have been proposed as determinant factors of non-responsiveness to the IFN-alpha/Ribavirin treatment and of liver fibrosis extension in patients with CHC and obesity.	Ribavirin	160-169	tumor necrosis factor	Homo sapiens	36-45	
16496340-4	2006	HRC 203 had greater anti-viral activity on both isolated hepatocytes and macrophages, whereas both ribavirin and HRC 203 inhibited production of the pro-inflammatory cytokines interferon gamma (IFN-gamma) and tumor necrosis factor alpha (TNF-alpha) by macrophages.	Ribavirin	99-108	tumor necrosis factor	Homo sapiens	209-236	
15328100-12	2004	Combination alpha interferon-ribavirin therapy may alter the cytokine profile of maturing DCs overall by suppressing IL-10 production but maintaining IL-12(p70) and TNF-alpha production, a pattern that would favor viral elimination through downstream effects on T cells.	Ribavirin	29-38	tumor necrosis factor	Homo sapiens	165-174	
12949432-0	2003	Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism.	Ribavirin	60-69	tumor necrosis factor	Homo sapiens	108-117	
15671755-0	2004	Changes in TNF-alpha mRNA levels in the peripheral blood of patients with chronic hepatitis C virus (HCV) infection during alpha-interferon and ribavirin therapy.	Ribavirin	144-153	tumor necrosis factor	Homo sapiens	11-20	
15671755-4	2004	In this study, we present the results of applying real-time RT-PCR for assessing the TNF-alpha mRNA level in the peripheral blood of patients treated with IFN-alpha and ribavirin.	Ribavirin	169-178	tumor necrosis factor	Homo sapiens	85-94	
15505595-8	2004	Ribavirin inhibited TNF-alpha, IFN-gamma, and IL-10 in both PHA and TT-stimulated PBMC at 100 microM (p <0.05).	Ribavirin	0-9	tumor necrosis factor	Homo sapiens	20-29	
12145664-4	2002	RESULTS: Using standard therapy in the presence and absence of ribavirin, the sustained responders had lower baseline tumor necrosis alpha (TNF-alpha) levels as compared to relapsed responders and non-responders.	Ribavirin	63-72	tumor necrosis factor	Homo sapiens	140-149	
12145664-6	2002	In pegylated combination therapy with high dose ribavirin, lower levels of TNF-alpha, transforming growth factor beta (TGF-beta) and fibrosis scores were seen when comparing baseline with follow up.	Ribavirin	48-57	tumor necrosis factor	Homo sapiens	75-84	
10190717-6	1999	RESULTS: Ribavirin enhanced a Type 1 (IL-2, IFNgamma, TNFalpha) while suppressing a Type 2 cytokine response (IL-4, IL-5 and IL-10), at the level of both protein and mRNA expression.	Ribavirin	9-18	tumor necrosis factor	Homo sapiens	54-62