PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8747782-5 1995 CCK-8-induced muscle strip contraction was atropine and tetrodotoxin resistant, but was completely eliminated by devazepide. Devazepide 113-123 cholecystokinin Canis lupus familiaris 0-3 8769975-8 1996 These studies demonstrate that L-364,718 has a dose dependent, inhibitory effect on basal, and OP-CCK-stimulated amylase secretion in a denervated autograft model. Devazepide 31-40 cholecystokinin Canis lupus familiaris 98-101 8661821-8 1996 Group 1 dogs received an intravenous bolus of MK329, a specific CCK receptor antagonist, at 20 nmol/kg after a standard mixed meal; group 2 colonic TVF dogs received a meal and an intravenous bolus of PYY polyclonal antibody at 1 mg/kg. Devazepide 46-51 cholecystokinin Canis lupus familiaris 64-67 8319843-4 1993 Nevertheless other CCK-related mechanisms may play an important role, since the administration of the highly specific CCK receptor antagonist MK-329 causes a marked reduction of the GRP-induced exocrine pancreatic secretion. Devazepide 142-148 cholecystokinin Canis lupus familiaris 19-22 7926458-6 1994 CCK-8 infused intravenously (0.1-1 microgram.kg-1.h-1) dose dependently increased the occurrence of relaxations while it was reduced by the CCK-A receptor antagonist devazepide but not the CCK-B antagonist L365260, both administered intravenously in a dose range of 0.1-100 micrograms/kg. Devazepide 166-176 cholecystokinin Canis lupus familiaris 0-3 7926458-8 1994 Both devazepide and L365260 (10 micrograms/kg) reduced the CCK-induced relaxations, but devazepide was more potent. Devazepide 5-15 cholecystokinin Canis lupus familiaris 59-62 7910794-5 1994 Blockade of type A CCK receptors with MK-329 (75 micrograms/kg, i.v.) Devazepide 38-44 cholecystokinin Canis lupus familiaris 19-22 8319843-4 1993 Nevertheless other CCK-related mechanisms may play an important role, since the administration of the highly specific CCK receptor antagonist MK-329 causes a marked reduction of the GRP-induced exocrine pancreatic secretion. Devazepide 142-148 cholecystokinin Canis lupus familiaris 118-121 1438992-2 1992 L364718 at a dose of 1.0 mg/kg was used as a specific and potent CCK receptor blocker, and its effect on spontaneous interdigestive motility and plasma motilin release were examined. Devazepide 0-7 cholecystokinin Canis lupus familiaris 65-68 1438992-4 1992 Whether the blocking effect of L364718 on CCK receptors was sufficient or not was verified by giving CCK-OP at a bolus dose of 10 ng/kg. Devazepide 31-38 cholecystokinin Canis lupus familiaris 42-45 1438992-7 1992 On the other hand, the effect of CCK-OP was completely abolished by pretreatment with L364718. Devazepide 86-93 cholecystokinin Canis lupus familiaris 33-36 2437283-0 1987 Roles of endogenous cholecystokinin in biliary, pancreatic and gastric function: studies with L-364,718, a specific cholecystokinin receptor antagonist. Devazepide 94-103 cholecystokinin Canis lupus familiaris 116-131 3441445-0 1987 L364718, a new CCK antagonist, inhibits biological actions of CCK in conscious dogs. Devazepide 0-7 cholecystokinin Canis lupus familiaris 15-18 3441445-0 1987 L364718, a new CCK antagonist, inhibits biological actions of CCK in conscious dogs. Devazepide 0-7 cholecystokinin Canis lupus familiaris 62-65 3441445-5 1987 This study demonstrates that L364718 acts as a potent antagonist of CCK"s action on pancreatic enzyme secretion and PP release in dogs and suggests that this agent might be a useful tool for studying the physiological role of CCK in conscious animals. Devazepide 29-36 cholecystokinin Canis lupus familiaris 68-71 3441445-5 1987 This study demonstrates that L364718 acts as a potent antagonist of CCK"s action on pancreatic enzyme secretion and PP release in dogs and suggests that this agent might be a useful tool for studying the physiological role of CCK in conscious animals. Devazepide 29-36 cholecystokinin Canis lupus familiaris 226-229 2135899-7 1990 Pretreatment with a highly selective CCK-receptor antagonist L-364 718 (1 mg/kg i.v.) Devazepide 61-70 cholecystokinin Canis lupus familiaris 37-40