PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16331685-2	2006	In this report we provide evidences that oleandrin, a cardiac glycoside potentially inhibited IL-8-, formyl peptide (FMLP)-, EGF-, or nerve growth factor (NGF)-, but not IL-1- or TNF-induced NF-kappaB activation in macrophages.	oleandrin	41-50	C-X-C motif chemokine ligand 8	Homo sapiens	94-98	
16331685-3	2006	Oleandrin inhibited IL-8-, but not TNF-induced NF-kappaB-dependent genes expression.	oleandrin	0-9	C-X-C motif chemokine ligand 8	Homo sapiens	20-24	
16331685-4	2006	Oleandrin inhibited the binding of IL-8, EGF, or NGF, but not IL-1 or TNF.	oleandrin	0-9	C-X-C motif chemokine ligand 8	Homo sapiens	35-39	
16331685-7	2006	Phospholipids significantly protected oleandrin-mediated inhibition of IL-8 binding thereby restoring IL-8-induced NF-kappaB activation.	oleandrin	38-47	C-X-C motif chemokine ligand 8	Homo sapiens	71-75	
16331685-7	2006	Phospholipids significantly protected oleandrin-mediated inhibition of IL-8 binding thereby restoring IL-8-induced NF-kappaB activation.	oleandrin	38-47	C-X-C motif chemokine ligand 8	Homo sapiens	102-106	
16331685-9	2006	Overall, our results suggest that oleandrin inhibits IL-8-mediated biological responses in diverse cell types by modulating IL-8Rs through altering membrane fluidity and microviscosity.	oleandrin	34-43	C-X-C motif chemokine ligand 8	Homo sapiens	53-57	
24172227-0	2014	Short-term exposure to oleandrin enhances responses to IL-8 by increasing cell surface IL-8 receptors.	oleandrin	23-32	C-X-C motif chemokine ligand 8	Homo sapiens	55-59	
24172227-0	2014	Short-term exposure to oleandrin enhances responses to IL-8 by increasing cell surface IL-8 receptors.	oleandrin	23-32	C-X-C motif chemokine ligand 8	Homo sapiens	87-91	
24172227-4	2014	Here, we studied the effects of the plant glycoside oleandrin on responses to IL-8 in a human monocytic cell line.	oleandrin	52-61	C-X-C motif chemokine ligand 8	Homo sapiens	78-82	
24172227-10	2014	Pulse exposure to oleandrin increased expression of IL-8 receptors and chemotaxis, release of enzymes and activation of NF-kappaB, NFAT and AP-1 along with increased IL-8-mediated calcineurin activation, and wound healing.	oleandrin	18-27	C-X-C motif chemokine ligand 8	Homo sapiens	52-56	
24172227-10	2014	Pulse exposure to oleandrin increased expression of IL-8 receptors and chemotaxis, release of enzymes and activation of NF-kappaB, NFAT and AP-1 along with increased IL-8-mediated calcineurin activation, and wound healing.	oleandrin	18-27	C-X-C motif chemokine ligand 8	Homo sapiens	166-170	
24172227-12	2014	CONCLUSIONS AND IMPLICATIONS: Short-term (1 h; pulse) exposure to a toxic glycoside oleandrin, enhanced biological responses to IL-8 in monocytic cells, without cytoxicity.	oleandrin	84-93	C-X-C motif chemokine ligand 8	Homo sapiens	128-132