PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28251581-3 2018 Chitin is sensed primarily in the lungs or gut where it activates a variety of innate (eosinophils, macrophages) and adaptive immune cells (IL-4/IL-13 expressing T helper type-2 lymphocytes). Chitin 0-6 interleukin 13 Homo sapiens 145-150 24631157-2 2014 We show that inhaled chitin induced expression of three epithelial cytokines, interleukin-25 (IL-25), IL-33, and thymic stromal lymphopoietin (TSLP), which nonredundantly activated resident innate lymphoid type 2 cells (ILC2s) to express IL-5 and IL-13 necessary for accumulation of eosinophils and alternatively activated macrophages (AAMs). Chitin 21-27 interleukin 13 Homo sapiens 247-252 21054166-4 2011 Acidic mammalian chitinase (AMCase) inhibits chitin-induced innate inflammation; augments chitin-free, allergen-induced Th2 inflammation; and mediates effector functions of IL-13. Chitin 17-23 interleukin 13 Homo sapiens 173-178