PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27136586-0	2016	Ovatodiolide Inhibits Breast Cancer Stem/Progenitor Cells through SMURF2-Mediated Downregulation of Hsp27.	ovatodiolide	0-12	SMAD specific E3 ubiquitin protein ligase 2	Homo sapiens	66-72	
27136586-8	2016	Overexpression of Hsp27 or knockdown of SMURF2 in AS-B145 cells diminished the therapeutic effect of ovatodiolide in the suppression of mammosphere formation.	ovatodiolide	101-113	SMAD specific E3 ubiquitin protein ligase 2	Homo sapiens	40-46	
27136586-9	2016	In summary, our data reveal that Ova displays an anti-CSC activity through SMURF2-mediated downregulation of Hsp27.	ovatodiolide	33-36	SMAD specific E3 ubiquitin protein ligase 2	Homo sapiens	75-81	
27136586-7	2016	Ova dose-dependently downregulated the expression of stemness genes, octamer-binding transcription factor 4 (Oct4) and Nanog, as well as heat shock protein 27 (Hsp27), but upregulated SMAD ubiquitin regulatory factor 2 (SMURF2) in mammosphere cells derived from AS-B145 or BT-474.	ovatodiolide	0-3	SMAD specific E3 ubiquitin protein ligase 2	Homo sapiens	184-218	
27136586-7	2016	Ova dose-dependently downregulated the expression of stemness genes, octamer-binding transcription factor 4 (Oct4) and Nanog, as well as heat shock protein 27 (Hsp27), but upregulated SMAD ubiquitin regulatory factor 2 (SMURF2) in mammosphere cells derived from AS-B145 or BT-474.	ovatodiolide	0-3	SMAD specific E3 ubiquitin protein ligase 2	Homo sapiens	220-226