PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3584134-4 1987 Upon reconstitution with NADPH-cytochrome P-450 reductase, the enzyme showed a high activity of cholesterol 7 alpha-hydroxylation with the turnover number of 50 min-1 at 37 degrees C. The reaction was inhibited neither by aminoglutethimide nor by metyrapone, but inhibited markedly by iodoacetamide and disulfiram. Disulfiram 303-313 cytochrome p450 oxidoreductase Rattus norvegicus 25-57