PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12954456-0 2003 Myo-inositol restores the inflammation-induced down-regulation of taurine transport by the murine macrophage cell line, RAW 264.7. Taurine 66-73 synaptopodin 2 Mus musculus 0-3 12954456-1 2003 The role of myo-inositol in the regulation of taurine transport in activated murine macrophage cell line, RAW 264.7, was studied. Taurine 46-53 synaptopodin 2 Mus musculus 12-15 12954456-4 2003 The protective role of myo-inositol against stress-induced down-regulation of taurine transport by macrophages was further investigated in conditions mimicking bacterial infection, inflammation, and immune-suppressed circumstances. Taurine 78-85 synaptopodin 2 Mus musculus 23-26 12954456-8 2003 Again, this inflammation-induced down-regulation of taurine transport activity was completely antagonized with co-administration of 100 nM or higher levels of myo-inositol in the culture medium. Taurine 52-59 synaptopodin 2 Mus musculus 159-162 12954456-9 2003 Similarly, myo-inositol effectively restored the taurine transport activity suppressed by cyclosporin A (0.5 and 50 nM) in murine macrophages (p < 0.01). Taurine 49-56 synaptopodin 2 Mus musculus 11-14 12954456-10 2003 From these results, myo-inositol appears to be a common accelerator of taurine transport by murine macrophages in diverse conditions of down-regulated taurine transport. Taurine 71-78 synaptopodin 2 Mus musculus 20-23 12954456-10 2003 From these results, myo-inositol appears to be a common accelerator of taurine transport by murine macrophages in diverse conditions of down-regulated taurine transport. Taurine 151-158 synaptopodin 2 Mus musculus 20-23