PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20471413-1 2010 In the present work, a new particulate controlled release system was prepared, by coating alginate-g-PCL/Ca(2+) beads with chitosan. Alginates 90-98 PHD finger protein 1 Homo sapiens 101-104 23602170-0 2013 Controlled release of metronidazole from composite poly-epsilon-caprolactone/alginate (PCL/alginate) rings for dental implants. Alginates 77-85 PHD finger protein 1 Homo sapiens 87-90 32260919-0 2013 Collagen/alginate scaffolds comprising core (PCL)-shell (collagen/alginate) struts for hard tissue regeneration: fabrication, characterisation, and cellular activities. Alginates 9-17 PHD finger protein 1 Homo sapiens 45-48 23602170-9 2013 The PCL/alginate agent release characteristic fits the Ritger-Peppas model indicating a diffusion-based mechanism during the 30-day study period. Alginates 8-16 PHD finger protein 1 Homo sapiens 4-7 25541639-6 2015 Due to the alginate components in the composites, the scaffolds showed significantly enhanced wetting behavior, water-absorption (~12-fold), and meaningful biological activities (~2.1-fold for cell-seeding efficiency, ~2.5-fold for cell-viability at 7 days, ~3.4-fold for calcium deposition), compared with a pure PCL scaffold. Alginates 11-19 PHD finger protein 1 Homo sapiens 314-317 19631739-1 2009 This paper presents the development of new pH-sensitive, amphiphilic and biocompatible hydrogels based on alginate-g-PCL, cross-linked with calcium ions to form beads, prepared for controlled delivery of poorly water-soluble drug. Alginates 106-114 PHD finger protein 1 Homo sapiens 117-120 19631739-4 2009 In both media, rates of swelling were lower for beads based on amphiphilic derivatives than for alginate/Ca2+ ones due to the hydrophobic PCL grafts, and decreased when hydrophobic character increased. Alginates 96-104 PHD finger protein 1 Homo sapiens 138-141 19631739-6 2009 The drug was protected in acidic fluid (only 14-20% of release for alginate-g-PCL hydrogel against 35% of release for alginate hydrogel during 350 min). Alginates 67-76 PHD finger protein 1 Homo sapiens 78-81 19631739-6 2009 The drug was protected in acidic fluid (only 14-20% of release for alginate-g-PCL hydrogel against 35% of release for alginate hydrogel during 350 min). Alginates 67-75 PHD finger protein 1 Homo sapiens 78-81 19631739-8 2009 PCL leads to decrease in the release kinetics in SIF (2h for alginate-g-PCL/Ca2+ beads against 1h for alginate/Ca2+ beads). Alginates 61-69 PHD finger protein 1 Homo sapiens 0-3 19631739-8 2009 PCL leads to decrease in the release kinetics in SIF (2h for alginate-g-PCL/Ca2+ beads against 1h for alginate/Ca2+ beads). Alginates 61-69 PHD finger protein 1 Homo sapiens 72-75 19631739-8 2009 PCL leads to decrease in the release kinetics in SIF (2h for alginate-g-PCL/Ca2+ beads against 1h for alginate/Ca2+ beads). Alginates 102-110 PHD finger protein 1 Homo sapiens 0-3 35323276-0 2022 PCL/Sodium-Alginate Based 3D-Printed Dual Drug Delivery System with Antibacterial Activity for Osteomyelitis Therapy. Alginates 4-19 PHD finger protein 1 Homo sapiens 0-3 35323276-5 2022 Thus, in this study, we developed a dual-drug-releasing PCL/sodium-alginate-based 3D-printed scaffold to effectively treat osteomyelitis by removing the biofilm. Alginates 60-75 PHD finger protein 1 Homo sapiens 56-59 24788192-4 2014 MATERIALS AND METHODS: The fabrication procedure for obtaining PCL/alginate/hUCS was performed. Alginates 67-75 PHD finger protein 1 Homo sapiens 63-66 24145300-10 2013 Based on these in vitro and in vivo results, the use of the PCL/alginate/BMP-2 scaffold seemed to be a promising technique for the mastoid obliteration. Alginates 64-72 PHD finger protein 1 Homo sapiens 60-63 24145300-6 2013 Furthermore, the PCL/alginate/BMP-2 scaffold showed significantly higher calcium deposition than the PCL/alginate scaffold. Alginates 21-29 PHD finger protein 1 Homo sapiens 17-20 24145300-6 2013 Furthermore, the PCL/alginate/BMP-2 scaffold showed significantly higher calcium deposition than the PCL/alginate scaffold. Alginates 105-113 PHD finger protein 1 Homo sapiens 17-20 24145300-8 2013 Confocal microscopic findings showed that the honeycomb appearance of the PCL structure remained in the control group (pure PCL), but significant amount of bone remodeling in the experimental group (PCL/alginate/BMP-2). Alginates 203-211 PHD finger protein 1 Homo sapiens 74-77