PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29162108-8 2017 Dexamethasone increased beta2-AR expression and enhanced the inhibitory effect of salmeterol on severe asthma fibrocyte differentiation. Dexamethasone 0-13 adrenoceptor beta 2 Homo sapiens 24-32 3033466-1 1987 Treatment of 3T3-L1 preadipocytes (fibroblasts) with 250 nM dexamethasone for 48 hr caused a doubling of total beta-adrenergic receptors and an increase in beta 2-adrenergic receptor subtype proportion from approximately 50% in controls to 85% in treated cells. Dexamethasone 60-73 adrenoceptor beta 2 Homo sapiens 156-182 7680566-5 1993 In A431 cells maintained after confluence in serum-free media for 72 h, maximal beta 2AR mRNA levels in response to 10% fetal bovine serum were 85% of maximal levels following serum plus 10 microM dexamethasone. Dexamethasone 197-210 adrenoceptor beta 2 Homo sapiens 80-88 33032603-0 2020 Dexamethasone rescues TGF-beta1-mediated beta2-adrenergic receptor dysfunction and attenuates phosphodiesterase 4D expression in human airway smooth muscle cells. Dexamethasone 0-13 adrenoceptor beta 2 Homo sapiens 41-66 18774166-8 2008 Dexamethasone pretreatment of PCLSs (1 hour) prevented albuterol-induced beta(2)-AR desensitization by increasing the maximum drug effect (P = .0023) and decreasing the log half-maximum effective concentration values (P < .0001) from that of albuterol alone. Dexamethasone 0-13 adrenoceptor beta 2 Homo sapiens 73-83 23968846-5 2013 GC receptor (GR) mRNA decreased and beta2 adrenergic receptor (beta 2AR) mRNA increased significantly after 24 h exposure to DEX. Dexamethasone 125-128 adrenoceptor beta 2 Homo sapiens 36-61 23968846-5 2013 GC receptor (GR) mRNA decreased and beta2 adrenergic receptor (beta 2AR) mRNA increased significantly after 24 h exposure to DEX. Dexamethasone 125-128 adrenoceptor beta 2 Homo sapiens 63-71 19783788-10 2010 Pretreatment of HBECs and Beas-2B cells but not human airway smooth muscle cells with the corticosteroids dexamethasone or fluticasone abolished virus-mediated beta(2)AR loss of function. Dexamethasone 106-119 adrenoceptor beta 2 Homo sapiens 160-169 11897997-4 2002 OBJECTIVE: We examined the effects of dexamethasone (DEX) on beta(2)AR gene expression and the function of the beta(2)AR-AC system in cultured human airway epithelial cells. Dexamethasone 38-51 adrenoceptor beta 2 Homo sapiens 61-70 17901197-4 2008 In contrast, simple glucocorticoid response element (GRE)-dependent transcription induced by dexamethasone, budesonide, and fluticasone was synergistically enhanced by beta(2)-adrenoceptor agonists, including salmeterol and formoterol, to a level that could not be achieved by glucocorticoid alone. Dexamethasone 93-106 adrenoceptor beta 2 Homo sapiens 168-188 11897997-4 2002 OBJECTIVE: We examined the effects of dexamethasone (DEX) on beta(2)AR gene expression and the function of the beta(2)AR-AC system in cultured human airway epithelial cells. Dexamethasone 53-56 adrenoceptor beta 2 Homo sapiens 61-70 11897997-7 2002 The function of the beta(2)AR-AC system was assessed from cAMP production in response to the beta(2)-agonist isoproterenol and the expression of the stimulatory G protein G(alpha)s. RESULTS: DEX had no effect on beta-adrenergic receptor density or on the beta(1)/beta(2) ratio over a wide range of concentrations and exposure times. Dexamethasone 191-194 adrenoceptor beta 2 Homo sapiens 20-29 11897997-8 2002 However, DEX significantly but transiently enhanced beta(2)AR mRNA levels (approximately 1.5-fold) and beta(2)AR promoter activity (approximately 1.5-fold), indicating increased beta(2)AR gene transcription. Dexamethasone 9-12 adrenoceptor beta 2 Homo sapiens 52-61 11897997-8 2002 However, DEX significantly but transiently enhanced beta(2)AR mRNA levels (approximately 1.5-fold) and beta(2)AR promoter activity (approximately 1.5-fold), indicating increased beta(2)AR gene transcription. Dexamethasone 9-12 adrenoceptor beta 2 Homo sapiens 103-112 11897997-8 2002 However, DEX significantly but transiently enhanced beta(2)AR mRNA levels (approximately 1.5-fold) and beta(2)AR promoter activity (approximately 1.5-fold), indicating increased beta(2)AR gene transcription. Dexamethasone 9-12 adrenoceptor beta 2 Homo sapiens 103-112 9208139-0 1997 Protection by dexamethasone of the functional desensitization to beta 2-adrenoceptor-mediated responses in human lung mast cells. Dexamethasone 14-27 adrenoceptor beta 2 Homo sapiens 65-84 10784182-9 2000 Dexamethasone did not change the total betaAR number but tended to increase the beta1AR and beta2AR transcript concentrations. Dexamethasone 0-13 adrenoceptor beta 2 Homo sapiens 92-99