PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29162108-8	2017	Dexamethasone increased beta2-AR expression and enhanced the inhibitory effect of salmeterol on severe asthma fibrocyte differentiation.	Dexamethasone	0-13	adrenoceptor beta 2	Homo sapiens	24-32	
3033466-1	1987	Treatment of 3T3-L1 preadipocytes (fibroblasts) with 250 nM dexamethasone for 48 hr caused a doubling of total beta-adrenergic receptors and an increase in beta 2-adrenergic receptor subtype proportion from approximately 50% in controls to 85% in treated cells.	Dexamethasone	60-73	adrenoceptor beta 2	Homo sapiens	156-182	
7680566-5	1993	In A431 cells maintained after confluence in serum-free media for 72 h, maximal beta 2AR mRNA levels in response to 10% fetal bovine serum were 85% of maximal levels following serum plus 10 microM dexamethasone.	Dexamethasone	197-210	adrenoceptor beta 2	Homo sapiens	80-88	
33032603-0	2020	Dexamethasone rescues TGF-beta1-mediated beta2-adrenergic receptor dysfunction and attenuates phosphodiesterase 4D expression in human airway smooth muscle cells.	Dexamethasone	0-13	adrenoceptor beta 2	Homo sapiens	41-66	
18774166-8	2008	Dexamethasone pretreatment of PCLSs (1 hour) prevented albuterol-induced beta(2)-AR desensitization by increasing the maximum drug effect (P = .0023) and decreasing the log half-maximum effective concentration values (P < .0001) from that of albuterol alone.	Dexamethasone	0-13	adrenoceptor beta 2	Homo sapiens	73-83	
23968846-5	2013	GC receptor (GR) mRNA decreased and beta2 adrenergic receptor (beta 2AR) mRNA increased significantly after 24 h exposure to DEX.	Dexamethasone	125-128	adrenoceptor beta 2	Homo sapiens	36-61	
23968846-5	2013	GC receptor (GR) mRNA decreased and beta2 adrenergic receptor (beta 2AR) mRNA increased significantly after 24 h exposure to DEX.	Dexamethasone	125-128	adrenoceptor beta 2	Homo sapiens	63-71	
19783788-10	2010	Pretreatment of HBECs and Beas-2B cells but not human airway smooth muscle cells with the corticosteroids dexamethasone or fluticasone abolished virus-mediated beta(2)AR loss of function.	Dexamethasone	106-119	adrenoceptor beta 2	Homo sapiens	160-169	
11897997-4	2002	OBJECTIVE: We examined the effects of dexamethasone (DEX) on beta(2)AR gene expression and the function of the beta(2)AR-AC system in cultured human airway epithelial cells.	Dexamethasone	38-51	adrenoceptor beta 2	Homo sapiens	61-70	
17901197-4	2008	In contrast, simple glucocorticoid response element (GRE)-dependent transcription induced by dexamethasone, budesonide, and fluticasone was synergistically enhanced by beta(2)-adrenoceptor agonists, including salmeterol and formoterol, to a level that could not be achieved by glucocorticoid alone.	Dexamethasone	93-106	adrenoceptor beta 2	Homo sapiens	168-188	
11897997-4	2002	OBJECTIVE: We examined the effects of dexamethasone (DEX) on beta(2)AR gene expression and the function of the beta(2)AR-AC system in cultured human airway epithelial cells.	Dexamethasone	53-56	adrenoceptor beta 2	Homo sapiens	61-70	
11897997-7	2002	The function of the beta(2)AR-AC system was assessed from cAMP production in response to the beta(2)-agonist isoproterenol and the expression of the stimulatory G protein G(alpha)s. RESULTS: DEX had no effect on beta-adrenergic receptor density or on the beta(1)/beta(2) ratio over a wide range of concentrations and exposure times.	Dexamethasone	191-194	adrenoceptor beta 2	Homo sapiens	20-29	
11897997-8	2002	However, DEX significantly but transiently enhanced beta(2)AR mRNA levels (approximately 1.5-fold) and beta(2)AR promoter activity (approximately 1.5-fold), indicating increased beta(2)AR gene transcription.	Dexamethasone	9-12	adrenoceptor beta 2	Homo sapiens	52-61	
11897997-8	2002	However, DEX significantly but transiently enhanced beta(2)AR mRNA levels (approximately 1.5-fold) and beta(2)AR promoter activity (approximately 1.5-fold), indicating increased beta(2)AR gene transcription.	Dexamethasone	9-12	adrenoceptor beta 2	Homo sapiens	103-112	
11897997-8	2002	However, DEX significantly but transiently enhanced beta(2)AR mRNA levels (approximately 1.5-fold) and beta(2)AR promoter activity (approximately 1.5-fold), indicating increased beta(2)AR gene transcription.	Dexamethasone	9-12	adrenoceptor beta 2	Homo sapiens	103-112	
9208139-0	1997	Protection by dexamethasone of the functional desensitization to beta 2-adrenoceptor-mediated responses in human lung mast cells.	Dexamethasone	14-27	adrenoceptor beta 2	Homo sapiens	65-84	
10784182-9	2000	Dexamethasone did not change the total betaAR number but tended to increase the beta1AR and beta2AR transcript concentrations.	Dexamethasone	0-13	adrenoceptor beta 2	Homo sapiens	92-99