PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33050333-7 2020 In addition, DEX decreased protein stability of DR5 via GSK-3beta-mediated upregulation of Cbl, an E3 ligase of DR5. Dexamethasone 13-16 Cbl proto-oncogene Homo sapiens 91-94 33050333-8 2020 Knockdown of Cbl by siRNA markedly inhibited DEX-induced DR5 downregulation. Dexamethasone 45-48 Cbl proto-oncogene Homo sapiens 13-16 26206089-0 2015 miR-216a rescues dexamethasone suppression of osteogenesis, promotes osteoblast differentiation and enhances bone formation, by regulating c-Cbl-mediated PI3K/AKT pathway. Dexamethasone 17-30 Cbl proto-oncogene Homo sapiens 139-144 26206089-10 2015 Downregulation of c-Cbl by short hairpin RNAs can mimic the promotion effects of miR-216a and significantly rescue the suppressive effects of DEX on osteogenesis. Dexamethasone 142-145 Cbl proto-oncogene Homo sapiens 18-23