PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7955140-8 1994 Injection of dexamethasone into adrenalectomized rats acted within a day to increase ventricular Kv1.5 mRNA and immunoreactive protein approximately 50-fold and approximately 20-fold, respectively. Dexamethasone 13-26 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 97-102 8916900-5 1996 Dexamethasone treatment doubled expression of Kv1.5 homomeric channels but only modestly up-regulated Kv1.4/Kv1.5 heteromeric complexes. Dexamethasone 0-13 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 46-51 8916900-5 1996 Dexamethasone treatment doubled expression of Kv1.5 homomeric channels but only modestly up-regulated Kv1.4/Kv1.5 heteromeric complexes. Dexamethasone 0-13 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 108-113 8938730-0 1996 Dexamethasone and stress upregulate Kv1.5 K+ channel gene expression in rat ventricular myocytes. Dexamethasone 0-13 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 36-39 8938730-2 1996 Previous studies demonstrated that administration of dexamethasone, a glucocorticoid receptor agonist, to adrenalectomized rats, rapidly induces Kv1.5 K+ channel expression in the ventricle of the hear. Dexamethasone 53-66 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 145-148 8938730-7 1996 Increased Kv1.5 message also found in isolated ventricular cardiomyocytes following in vivo treatment with dexamethasone. Dexamethasone 107-120 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 10-15 8938730-9 1996 We conclude that dexamethasone induction of Kv1.5 gene is tissue-specific. Dexamethasone 17-30 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 44-49 7955140-10 1994 Furthermore, dexamethasone-induced upregulation was specific for Kv1.5, since whole-heart Kv1.4 and Kv2.1 mRNA levels, as well as ventricular Kv2.1 mRNA expression, were unchanged. Dexamethasone 13-26 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 65-70 7955140-11 1994 Thus, dexamethasone specifically upregulates Kv1.5 K+ channel gene expression in rat ventricle but not atrium. Dexamethasone 6-19 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 45-50 8352944-0 1993 Dexamethasone rapidly induces Kv1.5 K+ channel gene transcription and expression in clonal pituitary cells. Dexamethasone 0-13 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 30-35 8352944-2 1993 Here, we demonstrate that dexamethasone, a glucocorticoid agonist, rapidly induces Kv1.5 gene transcription, but does not affect Kv1.5 mRNA turnover (t1/2 approximately 0.5 hr) in GH3 cells. Dexamethasone 26-39 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 83-88 8081726-2 1993 Recently, we found that dexamethasone increases expression of Kv1.5 K+ channel mRNA in GH3 rat pituitary tumor cells. Dexamethasone 24-37 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 62-67 8081726-4 1993 Here we report that dexamethasone treatment of GH3 cells for 3 hours increases Kv1.5 mRNA without affecting Kv1.4 or Kv2.1 K+ channel mRNAs or D Ca2+ channel mRNA. Dexamethasone 20-33 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 79-84 8081726-7 1993 We then tested whether Kv1.5 mRNA is induced by dexamethasone in normal rat pituitary cells. Dexamethasone 48-61 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 23-28 8081726-9 1993 One day following dexamethasone injection Kv1.5 mRNA was increased 8-fold. Dexamethasone 18-31 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 42-47 8081726-10 1993 Dexamethasone induction of Kv1.5 mRNA was also found in primary cultured anterior pituitary cells. Dexamethasone 0-13 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 27-32 35354756-4 2022 DEX induced immediate and transient increase in the mRNA level of Kv1.5 and Kir2.2 with peaks at 6 (5.0 fold) and 3 hours (3.3 fold) after DEX injection, respectively. Dexamethasone 0-3 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 66-71 35354756-4 2022 DEX induced immediate and transient increase in the mRNA level of Kv1.5 and Kir2.2 with peaks at 6 (5.0 fold) and 3 hours (3.3 fold) after DEX injection, respectively. Dexamethasone 139-142 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 66-71 1791837-5 1991 Dexamethasone rapidly increased the steady state concentration of Kv1 mRNA in GH3 cells in a dose-dependent manner. Dexamethasone 0-13 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 66-69