PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23935943-6	2013	Cardiac AT1aR, Bax, and IGF-1 mRNA expression was significantly increased by DEX compared to SAL at E17.5.	Dexamethasone	77-80	BCL2-associated X protein	Mus musculus	15-18	
22442678-5	2012	Furthermore, ablation of Bax in female mice protected against Dexa-induced bone growth impairment.	Dexamethasone	62-66	BCL2-associated X protein	Mus musculus	25-28	
21622206-6	2011	The expression levels of Bcl-2 and Bax, which regulate the mitochondria-initiated apoptotic cascade signaling pathway, were significantly different in response to Dex and hypoxia.	Dexamethasone	163-166	BCL2-associated X protein	Mus musculus	35-38	
16916958-3	2006	Our group previously demonstrated that in the thymus, MEL inhibits the release of Cytochrome C from mitochondria and the dexamethasone-dependent increase of bax mRNA levels.	Dexamethasone	121-134	BCL2-associated X protein	Mus musculus	157-160	
20889222-8	2010	Exendin-4 down-regulated caspase 3 activity, reduced cytochrome c levels in cytoplasm, and increased Bcl-2 protein levels and the Bcl-2 to Bax ratio in dexamethasone-treated beta-cells.	Dexamethasone	152-165	BCL2-associated X protein	Mus musculus	139-142	
19995710-0	2009	Dexamethasone effects on Bax expression in the mouse testicular germ cells.	Dexamethasone	0-13	BCL2-associated X protein	Mus musculus	25-28	
19995710-2	2009	The aim of the present study was to find out whether dexamethasone (Dex), a widely used GC, would influence the apoptosis and expression of Bax, an important proapoptotic protein, in the mouse testicular germ cells.	Dexamethasone	53-66	BCL2-associated X protein	Mus musculus	140-143	
19995710-2	2009	The aim of the present study was to find out whether dexamethasone (Dex), a widely used GC, would influence the apoptosis and expression of Bax, an important proapoptotic protein, in the mouse testicular germ cells.	Dexamethasone	68-71	BCL2-associated X protein	Mus musculus	140-143	
9108035-4	1997	Induction of apoptosis in murine thymocytes by dexamethasone or gamma-irradiation shifts the subcellular locations of Bax and Bcl-X(L) from soluble to membrane-bound forms.	Dexamethasone	47-60	BCL2-associated X protein	Mus musculus	118-121	
15987750-10	2005	Dexamethasone also lowered the increase in the proapoptotic Bax, which was increased by PA, and increased expression of the antiapoptotic Bcl-xL protein.	Dexamethasone	0-13	BCL2-associated X protein	Mus musculus	60-63	
12039857-5	2002	Although dexamethasone induced transcription of the proapoptotic gene bax, there was no increase of Bax protein levels.	Dexamethasone	9-22	BCL2-associated X protein	Mus musculus	70-73	
9108035-6	1997	Inhibition of apoptosis with cycloheximide inhibits the movement of Bax and Bcl-X(L) in thymocytes from the cytosol into membranes induced by dexamethasone treatment.	Dexamethasone	142-155	BCL2-associated X protein	Mus musculus	68-71	
32709024-7	2020	Quercetin can protect against dexamethasone-induced muscle atrophy by regulating the Bax/Bcl-2 ratio at the protein level and abnormal DeltaPsim, which leads to the suppression of apoptosis.	Dexamethasone	30-43	BCL2-associated X protein	Mus musculus	85-88	
34638536-10	2021	Western blot was performed to determine the levels of p-ERK1/2, Bcl-XL, Bax, and Hsp70 proteins upon DEX or DEX plus colostrum exposure.	Dexamethasone	101-104	BCL2-associated X protein	Mus musculus	72-75	
34638536-10	2021	Western blot was performed to determine the levels of p-ERK1/2, Bcl-XL, Bax, and Hsp70 proteins upon DEX or DEX plus colostrum exposure.	Dexamethasone	108-111	BCL2-associated X protein	Mus musculus	72-75	
34638536-12	2021	Cells, upon colostrum co-treated with DEX, exhibited higher levels of p-ERK1/2 and lower levels of Bcl-XL, Bax, and Hsp70.	Dexamethasone	38-41	BCL2-associated X protein	Mus musculus	107-110	
35529482-10	2022	Dex inhibited MC3T3-E1 cell viability in a dose-dependent effect and induced apoptosis by increasing the expression levels of FOXO1, Bax, cleaved-Caspase-3, and cleaved-Caspase-9, while reducing the expression of Bcl-2.	Dexamethasone	0-3	BCL2-associated X protein	Mus musculus	133-136	
34675808-6	2021	In addition, kaempferol attenuated DEX-induced reduction of cyclin D1 and Bcl-2 expression and elevation of p53 and Bax expression.	Dexamethasone	35-38	BCL2-associated X protein	Mus musculus	116-119	
34223821-9	2021	Furthermore, dexamethasone stimulated pro-apoptotic signaling including superoxide production, caspase-8, -9, and -3 activities, NF- B, and Bax, but repressed the anti-apoptotic protein, Bcl-2.	Dexamethasone	13-26	BCL2-associated X protein	Mus musculus	140-143	
31786295-4	2020	Moreover, DEX-induced increase of Bax, cytochrome c and caspase-3, as well as decrease of Bcl-2, Wnt3, beta-catenin and c-Myc protein expression in MC3T3-E1 cells were also reversed.	Dexamethasone	10-13	BCL2-associated X protein	Mus musculus	34-37	
31844611-13	2019	In addition, Dex significantly increased Bax expression and reduced Bcl-2 expression.	Dexamethasone	13-16	BCL2-associated X protein	Mus musculus	41-44	
32513923-4	2020	When these triple mutant lines were exposed to dexamethasone for 10 days, they arrested, but after dexamethasone was removed, they had 10-fold higher clone forming efficiency than Bax/Bak1 double knock-out cells.	Dexamethasone	47-60	BCL2-associated X protein	Mus musculus	180-183	
30537677-15	2019	Knockdown of GSK3beta alleviated Dex-induced osteoblast and MC3T3-E1 cell apoptosis by decreasing the expressions of Bax, cleaved-caspase 3, cleaved-caspase 9 and increasing the expression of Bcl-2.	Dexamethasone	33-36	BCL2-associated X protein	Mus musculus	117-120	
30112029-7	2018	ECH or PFT-alpha treatment also alleviated dexamethasone"s action of inhibiting Bcl-2 expression as well as dexamethasone"s action of stimulating on the expression of p53 and Bax.	Dexamethasone	108-121	BCL2-associated X protein	Mus musculus	175-178	
29484386-7	2018	In addition, pretreatment with mangiferin markedly reduced Dex-induced BMP2 and p-Smad-1 downregulation, and corrected the expression of differentiation- and apoptosis-associated markers, including alkaline phosphatase, OSX, OCN, OPG, RANK, RANKL, Bcl-2 and Bax, which were altered by Dex treatment.	Dexamethasone	59-62	BCL2-associated X protein	Mus musculus	258-261	
27678165-8	2017	In addition, the protein expression levels of cleaved Caspase-3 and Bax increased and the protein expression level of Bcl-2 decreased in MC3T3-E1 cells exposed to Dex.	Dexamethasone	163-166	BCL2-associated X protein	Mus musculus	68-71