PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21289076-6	2011	The CYP2C8 inhibitors gemfibrozil 1-O-beta glucuronide and trimethoprim inhibited the depletion of 0.02 muM montelukast and formation of M6 from 0.05 muM montelukast more potently than did the CYP2C9 inhibitor sulfaphenazole.	Sulfaphenazole	210-224	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	4-10	
18776712-8	2008	Sulfaphenazole, an inhibitor of CYP2C8/2C9 suppressed luciferase promoter activity with the hypoxia response element (HRE) of VEGF in HUAEC.	Sulfaphenazole	0-14	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	32-38	
10510156-8	1999	Sulphaphenazole caused limited inhibition (<30%) of both pathways in human liver microsomes and microsomes from cells transfected with CYP2C9 cDNA were able to mediate the metabolism of rosiglitazone, in particular the N-demethylation pathway, albeit at a much slower rate than CYP2C8.	Sulfaphenazole	0-15	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	281-287	
15581350-4	2004	Twenty CYP2C8 site-directed mutants were constructed and expressed in yeast to compare their catalytic activities using five CYP2C8 substrates that exhibit different structures and sizes [paclitaxel, fluvastatin, retinoic acid, a sulfaphenazole derivative (DMZ), and diclofenac].	Sulfaphenazole	230-244	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	7-13