PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34999842-0 2022 Nicaraven mitigates radiation-induced lung injury by downregulating the NF-kappaB and TGF-beta/Smad pathways to suppress the inflammatory response. nicaraven 0-9 transforming growth factor alpha Mus musculus 86-94 34999842-7 2022 Western blot analysis showed that nicaraven administration effectively attenuated the radiation-induced upregulation of NF-kappaB, TGF-beta, and pSmad2 in lungs. nicaraven 34-43 transforming growth factor alpha Mus musculus 131-139 34999842-9 2022 In conclusion we find that nicaraven can effectively mitigate RILI by downregulating NF-kappaB and TGF-beta/pSmad2 pathways to suppress the inflammatory response in the irradiated lungs. nicaraven 27-36 transforming growth factor alpha Mus musculus 99-107