PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33356884-0 2021 Nicaraven inhibits TNFalpha-induced endothelial activation and inflammation through suppressing NF-kappaB signaling pathway. nicaraven 0-9 nuclear factor kappa B subunit 1 Homo sapiens 96-105 33356884-8 2021 Mechanistically, Nicaraven prevented TNFalpha-induced activation of NF-kappaB signaling pathway by suppressing the phosphorylation of NF-kappaB p65, IkappaBalpha, and IKKalpha/beta, stabilizing IkappaBalpha, and inhibiting the translocation of p65 from cytosol to nucleus. nicaraven 17-26 nuclear factor kappa B subunit 1 Homo sapiens 68-77 33356884-10 2021 Our findings indicated that Nicaraven effectively inhibits TNFalpha-induced endothelial activation and inflammatory response at least partly through inhibiting NF-kappaB signaling pathway. nicaraven 28-37 nuclear factor kappa B subunit 1 Homo sapiens 160-169