PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28616865-11 2017 Isoacteoside blocked LPS-induced TLR4 dimerization, resulting in a reduction in the recruitment of MyD88 and TIR-domain-containing adapter-inducing interferon-beta (TRIF) and the phosphorylation of TGF-beta-activated kinase-1 (TAK1). isoacteoside 0-12 myeloid differentiation primary response gene 88 Mus musculus 99-104 28616865-13 2017 CONCLUSIONS AND IMPLICATIONS: Isoacteoside blocked TLR4 dimerization, which activates the MyD88-TAK1-NF-kappaB/MAPK signalling cascades and TRIF pathway. isoacteoside 30-42 myeloid differentiation primary response gene 88 Mus musculus 90-95