PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31226569-0	2019	MnFe2O4 nanoparticles accelerate the clearance of mutant huntingtin selectively through ubiquitin-proteasome system.	manganese ferrite	0-7	huntingtin	Homo sapiens	57-67	
31226569-4	2019	Herein, we have synthesized biocompatible MnFe2O4 nanoparticles (NPs) and demonstrated their unique effect in accelerating the clearance of mutant huntingtin (Htt) protein exhibiting 74 glutamine repeats [Htt(Q74)].	manganese ferrite	42-49	huntingtin	Homo sapiens	147-157	
31226569-4	2019	Herein, we have synthesized biocompatible MnFe2O4 nanoparticles (NPs) and demonstrated their unique effect in accelerating the clearance of mutant huntingtin (Htt) protein exhibiting 74 glutamine repeats [Htt(Q74)].	manganese ferrite	42-49	huntingtin	Homo sapiens	159-162	
31226569-4	2019	Herein, we have synthesized biocompatible MnFe2O4 nanoparticles (NPs) and demonstrated their unique effect in accelerating the clearance of mutant huntingtin (Htt) protein exhibiting 74 glutamine repeats [Htt(Q74)].	manganese ferrite	42-49	huntingtin	Homo sapiens	205-208	
31226569-5	2019	UPS, rather than autophagy, was responsible for the efficient Htt(Q74) degradation facilitated by MnFe2O4 NPs.	manganese ferrite	98-105	huntingtin	Homo sapiens	62-65	
31226569-6	2019	Meanwhile, we demonstrated that MnFe2O4 NPs enhanced K48-linked ubiquitination of GFP-Htt(Q74).	manganese ferrite	32-39	huntingtin	Homo sapiens	86-89	
31226569-7	2019	Moreover, ubiqinlin-1, but not p62/SQSTM1, served as the ubiquitin receptor that mediated the enhanced degradation of Htt(Q74) by MnFe2O4 NPs.	manganese ferrite	130-137	huntingtin	Homo sapiens	118-121