PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15693841-9 2005 VWF interaction with platelet receptors GPIb and alphaIIbbeta3 was assessed adding aurin tricarboxylic acid (ATA) and anti-alphaIIbbeta3 antibody to blood before perfusion. Aurintricarboxylic Acid 83-107 von Willebrand factor Homo sapiens 0-3 18957047-10 2008 Moreover, ATA abolished thrombin-induced vWF secretion as well as complement activation. Aurintricarboxylic Acid 10-13 von Willebrand factor Homo sapiens 41-44 18957047-14 2008 CONCLUSIONS: Our study demonstrated in vitro protective effect of ATA on the inhibition of endothelial activation and vWF secretion and confirmed detrimental effect of ATA on induction of endothelial TF and platelet activation. Aurintricarboxylic Acid 66-69 von Willebrand factor Homo sapiens 118-121 15693841-9 2005 VWF interaction with platelet receptors GPIb and alphaIIbbeta3 was assessed adding aurin tricarboxylic acid (ATA) and anti-alphaIIbbeta3 antibody to blood before perfusion. Aurintricarboxylic Acid 109-112 von Willebrand factor Homo sapiens 0-3 21043709-8 1995 In addition, aurintricarboxylic acid, Evans blue and fucoidan all inhibited binding of vWF to both heparin and sulfatides with similar ICso values. Aurintricarboxylic Acid 13-36 von Willebrand factor Homo sapiens 87-90 9459348-5 1998 This epitope was found to be conformational and overlapping with vWF binding sites for aurin tricarboxylic acid (ATA), but not for botrocetin and heparin. Aurintricarboxylic Acid 87-111 von Willebrand factor Homo sapiens 65-68 9459348-5 1998 This epitope was found to be conformational and overlapping with vWF binding sites for aurin tricarboxylic acid (ATA), but not for botrocetin and heparin. Aurintricarboxylic Acid 113-116 von Willebrand factor Homo sapiens 65-68 9459349-5 1998 Both the binding of mutated rvWFs to platelets and platelet aggregation induced by type 2B rvWFs are inhibited by monoclonal anti-GPIb and anti-vWF antibodies, inhibitors of vWF binding to platelets in the presence of ristocetin, as well as by aurin tricarboxylic acid. Aurintricarboxylic Acid 244-268 von Willebrand factor Homo sapiens 29-32 9459349-5 1998 Both the binding of mutated rvWFs to platelets and platelet aggregation induced by type 2B rvWFs are inhibited by monoclonal anti-GPIb and anti-vWF antibodies, inhibitors of vWF binding to platelets in the presence of ristocetin, as well as by aurin tricarboxylic acid. Aurintricarboxylic Acid 244-268 von Willebrand factor Homo sapiens 92-95 9164855-4 1997 The anti-(human vWF A1 domain) monoclonal antibody (AJvW-2), as well as aurin tricarboxylic acid (ATA), at concentrations that saturate the vWF A1 domain, also inhibited this binding. Aurintricarboxylic Acid 72-96 von Willebrand factor Homo sapiens 140-143 7592056-6 1995 The physico-chemical properties of the sulfobacins indicate that their structures are completely different from that of aurintricarboxylic acid, the one known vWF receptor antagonist. Aurintricarboxylic Acid 120-143 von Willebrand factor Homo sapiens 159-162 12483465-2 2002 This study examined the functional significance of these polymorphisms in platelet reactivity and sensitivity to aurintricarboxylic acid (the antagonist of von Willebrand factor, vWF). Aurintricarboxylic Acid 113-136 von Willebrand factor Homo sapiens 179-182 9066012-12 1997 Since aurin tricarboxylic acid, which blocks the GPIb binding domain on vWF, was also found to completely block aggregation in Poiseuille flow, we conclude that it too affects the GPIIb-IIIa interaction. Aurintricarboxylic Acid 6-30 von Willebrand factor Homo sapiens 72-75 1412166-1 1992 Aurin tricarboxylic acid (ATA) is a potent inhibitor of ristocetin-mediated platelet agglutination and of shear-induced, von Willebrand factor (vWf)-mediated platelet aggregation, probably via inhibition of vWf interaction with glycoprotein Ib (GPIb). Aurintricarboxylic Acid 0-24 von Willebrand factor Homo sapiens 121-142 1287886-0 1992 Aurin tricarboxylic acid inhibits platelet adhesion to collagen by binding to the 509-695 disulphide loop of von Willebrand factor and competing with glycoprotein Ib. Aurintricarboxylic Acid 0-24 von Willebrand factor Homo sapiens 109-130 1287886-5 1992 ATA completely abolished vWF-dependent platelet agglutination induced by ristocetin, botrocetin and asialo-vWF, respectively. Aurintricarboxylic Acid 0-3 von Willebrand factor Homo sapiens 25-28 1287886-5 1992 ATA completely abolished vWF-dependent platelet agglutination induced by ristocetin, botrocetin and asialo-vWF, respectively. Aurintricarboxylic Acid 0-3 von Willebrand factor Homo sapiens 107-110 1412166-1 1992 Aurin tricarboxylic acid (ATA) is a potent inhibitor of ristocetin-mediated platelet agglutination and of shear-induced, von Willebrand factor (vWf)-mediated platelet aggregation, probably via inhibition of vWf interaction with glycoprotein Ib (GPIb). Aurintricarboxylic Acid 0-24 von Willebrand factor Homo sapiens 144-147 1412166-1 1992 Aurin tricarboxylic acid (ATA) is a potent inhibitor of ristocetin-mediated platelet agglutination and of shear-induced, von Willebrand factor (vWf)-mediated platelet aggregation, probably via inhibition of vWf interaction with glycoprotein Ib (GPIb). Aurintricarboxylic Acid 0-24 von Willebrand factor Homo sapiens 207-210 1412166-1 1992 Aurin tricarboxylic acid (ATA) is a potent inhibitor of ristocetin-mediated platelet agglutination and of shear-induced, von Willebrand factor (vWf)-mediated platelet aggregation, probably via inhibition of vWf interaction with glycoprotein Ib (GPIb). Aurintricarboxylic Acid 26-29 von Willebrand factor Homo sapiens 121-142 1412166-1 1992 Aurin tricarboxylic acid (ATA) is a potent inhibitor of ristocetin-mediated platelet agglutination and of shear-induced, von Willebrand factor (vWf)-mediated platelet aggregation, probably via inhibition of vWf interaction with glycoprotein Ib (GPIb). Aurintricarboxylic Acid 26-29 von Willebrand factor Homo sapiens 144-147 1412166-1 1992 Aurin tricarboxylic acid (ATA) is a potent inhibitor of ristocetin-mediated platelet agglutination and of shear-induced, von Willebrand factor (vWf)-mediated platelet aggregation, probably via inhibition of vWf interaction with glycoprotein Ib (GPIb). Aurintricarboxylic Acid 26-29 von Willebrand factor Homo sapiens 207-210 1611079-9 1992 Aurin tricarboxylic acid, which blocks the GPIb recognition site on the vWF monomer, and 6D1, a monoclonal antibody to GPIb, also completely inhibited platelet responses to shear stress. Aurintricarboxylic Acid 0-24 von Willebrand factor Homo sapiens 72-75 3264193-0 1988 Aurin tricarboxylic acid: a novel inhibitor of the association of von Willebrand factor and platelets. Aurintricarboxylic Acid 0-24 von Willebrand factor Homo sapiens 66-87 3264193-3 1988 A triphenyl-methyl compound, aurin tricarboxylic acid (ATA), inhibits shear-induced, vWF-mediated platelet aggregation in platelet-rich plasma (PRP) in concentrations above 200 mumol/L and in buffer suspensions of washed platelets at a concentration of 0.1 mumol/L. Aurintricarboxylic Acid 29-53 von Willebrand factor Homo sapiens 85-88 3264193-3 1988 A triphenyl-methyl compound, aurin tricarboxylic acid (ATA), inhibits shear-induced, vWF-mediated platelet aggregation in platelet-rich plasma (PRP) in concentrations above 200 mumol/L and in buffer suspensions of washed platelets at a concentration of 0.1 mumol/L. Aurintricarboxylic Acid 55-58 von Willebrand factor Homo sapiens 85-88 3264193-4 1988 In a concentration-dependent manner, ATA also inhibits ristocetin-induced, vWF-mediated platelet clumping in both fresh and formaldehyde-fixed platelet suspensions. Aurintricarboxylic Acid 37-40 von Willebrand factor Homo sapiens 75-78