PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33432230-4 2021 We find that a continuously high level of IL-2 leads to the persistent activation of STAT5 in CD8+ T cells, which in turn induces strong expression of tryptophan hydroxylase 1, thus catalyzing the conversion to tryptophan to 5-hydroxytryptophan (5-HTP). 5-Hydroxytryptophan 225-244 interleukin 2 Homo sapiens 42-46 33432230-4 2021 We find that a continuously high level of IL-2 leads to the persistent activation of STAT5 in CD8+ T cells, which in turn induces strong expression of tryptophan hydroxylase 1, thus catalyzing the conversion to tryptophan to 5-hydroxytryptophan (5-HTP). 5-Hydroxytryptophan 246-251 interleukin 2 Homo sapiens 42-46