PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26395757-5	2015	Meanwhile, two different zincs inhibited the ZEA-induced loss of mitochondrial membrane potential and elevation of late-stage apoptosis via activating the mitochondrial apoptotic pathway by recovering the mRNA and protein expression of pro-apoptotic genes (Bax, Casp3, Casp9).	Zearalenone	45-48	BCL2-associated X protein	Mus musculus	257-260	
28641471-11	2017	ZEA treatment also led to increased apoptosis in the spleen and Peyer"s patches; these changes were associated with changes in the ratios of Bax:Bcl-2.	Zearalenone	0-3	BCL2-associated X protein	Mus musculus	141-144	
27286704-5	2016	Immunoblotting and real-time quantitative polymerase chain reaction (RT-qPCR) revealed that ZEA treatment increased the ratio of Bax/Bcl-2.	Zearalenone	92-95	BCL2-associated X protein	Mus musculus	129-132	
21767629-5	2011	ZEN treatment also results in the loss of mitochondrial membrane potential (MMP), mitochondrial changes in Bcl-2 and Bax proteins, and cytoplasmic release of cytochrome c and apoptosis-inducing factor (AIF).	Zearalenone	0-3	BCL2-associated X protein	Mus musculus	117-120	
20163293-0	2010	Gynostemma pentaphyllum protects mouse male germ cells against apoptosis caused by zearalenone via Bax and Bcl-2 regulation.	Zearalenone	83-94	BCL2-associated X protein	Mus musculus	99-102	
20163293-5	2010	Taken together, these results suggest that Gynostemma pentaphyllum protects against toxicity caused by Zearalenone through anti-oxidation and anti-apoptosis via the regulation of Bax and Bcl-2 expression.	Zearalenone	103-114	BCL2-associated X protein	Mus musculus	179-182	
33433546-4	2021	In one set of experiments, the primary cultured mouse ovarian GCs were co-treated with ZEA and Scu for 24 h. The results showed that Scu significantly alleviated ZEA-induced cell damage, restored cell cycle arrest, and inhibited apoptosis by reducing the ratio of cleaved-caspase-3, cleaved-PARP, and Bax/Bcl-2.	Zearalenone	87-90	BCL2-associated X protein	Mus musculus	301-304	
35202175-4	2022	In addition, the key proteins involved in apoptosis, cleaved caspase-3 and -8, BAD, BAX, and phosphorylation of p53 and ERK1/2, were significantly increased in ZEN-exposed GC-1 spg cells for 24 h, and cytochrome c was released from mitochondria by ZEN.	Zearalenone	160-163	BCL2-associated X protein	Mus musculus	84-87