PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18380009-5 2008 Experiments with the embryonic stem cell line, ESC-B5, disclose that CTN induces apoptosis via several mechanisms, including ROS generation, increased cytoplasmic free calcium levels, intracellular nitric oxide production, enhanced Bax/Bcl-2 ratio, loss of mitochondrial membrane potential, cytochrome c release, activation of caspase-9 and caspase-3, and p21-activated protein kinase 2 and c-Jun N-terminal protein kinase activation. Citrinin 69-72 BCL2-associated X protein Mus musculus 232-235 17331071-4 2007 Experiments in embryonic stem cells (ESC-B5) showed that CTN induces apoptosis via ROS (reactive oxygen species) generation, increased Bax/Bcl-2 ratio, loss of MMP (mitochondrial membrane potential), induction of cytochrome c release, and activation of caspase 3. Citrinin 57-60 BCL2-associated X protein Mus musculus 135-138