PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1320873-0 1992 Ethanol modulates epidermal growth factor-stimulated tyrosine kinase and phosphorylation of PLC-gamma 1. Ethanol 0-7 phospholipase C gamma 1 Homo sapiens 92-103 1320873-8 1992 Interestingly, ethanol treatment of A431 cells inhibited EGF-stimulated phosphorylation of PLC-gamma 1 which is a substrate for EGF receptor tyrosine kinase. Ethanol 15-22 phospholipase C gamma 1 Homo sapiens 91-102 1320873-9 1992 It is concluded that ethanol at low concentrations has significant modulatory effect on basal and EGF-stimulated tyrosine kinase, as well as PLC-gamma 1 phosphorylation. Ethanol 21-28 phospholipase C gamma 1 Homo sapiens 141-152 21463338-8 2011 Ethanol decreases tyrosine phosphorylation and activation of upstream signaling proteins PLCgamma1, LAT, ZAP70, and Lck. Ethanol 0-7 phospholipase C gamma 1 Homo sapiens 89-98 21463338-10 2011 Sucrose density gradient fractionation and confocal microscopy revealed that ethanol inhibited essential upstream lipid raft-mediated TCR-dependent signaling events, namely colocalization of Lck, ZAP70, LAT, and PLCgamma1 with plasma membrane lipid rafts. Ethanol 77-84 phospholipase C gamma 1 Homo sapiens 212-221