PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16288500-0 2006 Study of ethanol-induced conformational changes of holo and apo alpha-lactalbumin by spectroscopy and limited proteolysis. Ethanol 9-16 lactalbumin alpha Homo sapiens 64-81 16288500-4 2006 Near circular dichroism spectra of holo alpha-lactalbumin indicated that its tertiary structure was maintained in 20% ethanol whereas it was altered in 30 and 40% ethanol. Ethanol 118-125 lactalbumin alpha Homo sapiens 40-57 16288500-4 2006 Near circular dichroism spectra of holo alpha-lactalbumin indicated that its tertiary structure was maintained in 20% ethanol whereas it was altered in 30 and 40% ethanol. Ethanol 163-170 lactalbumin alpha Homo sapiens 40-57 16288500-6 2006 Holo alpha-lactalbumin was resistant to trypsinolysis in 0% ethanol, whereas it was easily hydrolyzed in 20 and 30% ethanol. Ethanol 60-67 lactalbumin alpha Homo sapiens 5-22 16288500-6 2006 Holo alpha-lactalbumin was resistant to trypsinolysis in 0% ethanol, whereas it was easily hydrolyzed in 20 and 30% ethanol. Ethanol 116-123 lactalbumin alpha Homo sapiens 5-22 9715667-0 1998 Ethanol-induced conformational transitions in holo-alpha-lactalbumin: spectral and calorimetric studies. Ethanol 0-7 lactalbumin alpha Homo sapiens 51-68 9715667-2 1998 Experimental results allow us to propose that in isothermal conditions alpha-lactalbumin undergoes a number of conformational transitions with increasing ethanol concentration: N<=>I<=>D<=>H. The existence of I-state was deduced from spectrofluorometric and near-uv CD data. Ethanol 154-161 lactalbumin alpha Homo sapiens 71-88 9715667-5 1998 However, calorimetric measurements provide data revealing only the two-state mechanism of alpha-lactalbumin unfolding in both water and in aqueous ethanol solutions. Ethanol 147-154 lactalbumin alpha Homo sapiens 90-107 9739563-1 1998 Spectroscopic and thermodynamic studies of holo-alpha-lactalbumin folding show that in hydro-ethanolic media this protein structure is subjected to at least three distinct transitions induced by ethanol. Ethanol 93-100 lactalbumin alpha Homo sapiens 48-65 29124776-0 2018 Field findings about milk ethanol stability: a first report of interrelationship between alpha-lactalbumin and lactose. Ethanol 26-33 lactalbumin alpha Homo sapiens 89-106 29124776-7 2018 alpha-Lactalbumin (alpha-La) was also associated with ethanol stability, and the higher the alpha-La percentage the lower were the chances of ethanol instability. Ethanol 54-61 lactalbumin alpha Homo sapiens 0-17 29124776-7 2018 alpha-Lactalbumin (alpha-La) was also associated with ethanol stability, and the higher the alpha-La percentage the lower were the chances of ethanol instability. Ethanol 54-61 lactalbumin alpha Homo sapiens 0-8 29124776-7 2018 alpha-Lactalbumin (alpha-La) was also associated with ethanol stability, and the higher the alpha-La percentage the lower were the chances of ethanol instability. Ethanol 54-61 lactalbumin alpha Homo sapiens 19-27 29124776-7 2018 alpha-Lactalbumin (alpha-La) was also associated with ethanol stability, and the higher the alpha-La percentage the lower were the chances of ethanol instability. Ethanol 142-149 lactalbumin alpha Homo sapiens 0-17 29124776-7 2018 alpha-Lactalbumin (alpha-La) was also associated with ethanol stability, and the higher the alpha-La percentage the lower were the chances of ethanol instability. Ethanol 142-149 lactalbumin alpha Homo sapiens 0-8 29124776-8 2018 CONCLUSION: The lower values of alpha-La in unstable milk samples might be related to lower content of lactose, as alpha-La promotes lactose synthesis, a key component for the osmotic balance of milk and thus its ethanol stability. Ethanol 213-220 lactalbumin alpha Homo sapiens 32-40 29124776-8 2018 CONCLUSION: The lower values of alpha-La in unstable milk samples might be related to lower content of lactose, as alpha-La promotes lactose synthesis, a key component for the osmotic balance of milk and thus its ethanol stability. Ethanol 213-220 lactalbumin alpha Homo sapiens 115-123 29124776-9 2018 This is the first field report linking ethanol stability indirectly with alpha-La. Ethanol 39-46 lactalbumin alpha Homo sapiens 73-81