PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23238299-3 2013 Chelidonine and the alkaloid extract inhibited P-gp/MDR1 activity in a concentration-dependent manner in Caco-2 and CEM/ADR5000 and reversed their doxorubicin resistance. chelidonine 0-11 phosphoglycolate phosphatase Homo sapiens 47-51 23238299-8 2013 Treatment of Caco-2 cells with 50 mug/ml alkaloid extract and 50 muM chelidonine for up to 48 h resulted in a significant decrease in mRNA levels of P-gp/MDR1, MRP1, BCRP, CYP3A4, GST, and hPXR and in a significant increase in caspase-3 and caspase-8 mRNA. chelidonine 69-80 phosphoglycolate phosphatase Homo sapiens 149-153