PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23238299-8 2013 Treatment of Caco-2 cells with 50 mug/ml alkaloid extract and 50 muM chelidonine for up to 48 h resulted in a significant decrease in mRNA levels of P-gp/MDR1, MRP1, BCRP, CYP3A4, GST, and hPXR and in a significant increase in caspase-3 and caspase-8 mRNA. chelidonine 69-80 caspase 8 Homo sapiens 241-250