PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7766635-2	1995	By screening a number of potential target sites for triple helix formation within mammalian genes that allow genetic selection in cell culture, we have identified a site within intron 1 of the hamster adenine phosphoribosyltransferase (APRT) gene that specifically binds a triplex-forming oligodeoxyribonucleotide (TFO) with high affinity.	tfo	315-318	adenine phosphoribosyltransferase	Homo sapiens	236-240	
7766635-4	1995	This high-affinity binding is very specific, as a 10(5)-fold excess of genomic DNA reduced triplex formation less than 10-fold, and within a 6928-bp plasmid bearing the APRT gene, only restriction fragments containing the intron 1 site were found to bind the TFO.	tfo	259-262	adenine phosphoribosyltransferase	Homo sapiens	169-173	
8718860-2	1996	To test the applicability of triple-helix formation as a means for achieving precisely timed site-specific damage within a mammalian gene, a triplex-forming oligodeoxyribonucleotide (TFO) that binds with high affinity to a specific site within the hamster adenine phosphoribosyltransferase (APRT) gene was modified with the photochemically reactive psoralen derivative 4"-(hydroxymethyl)-4,5",8-trimethylpsoralen (HMT).	tfo	183-186	adenine phosphoribosyltransferase	Homo sapiens	291-295	
8718860-3	1996	The modified TFO, psorTFO1, bound with high affinity to a target site within intron 1 of the APRT gene.	tfo	13-16	adenine phosphoribosyltransferase	Homo sapiens	93-97