PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19956887-5	2010	Treatment with TRAIL in combination with subtoxic concentrations of eupatolide enhanced the TRAIL-induced cytotoxicity in MCF-7, MDA-MB-231 and MDA-MB-453 breast cancer cells, whereas each reagent alone slightly induced cell death.	eupatolide	68-78	TNF superfamily member 10	Homo sapiens	92-97	
19956887-13	2010	Taken together, these results indicate that eupatolide could augment TRAIL-induced apoptosis in human breast cancer cells by down-regulating c-FLIP expression through the inhibition of AKT phosphorylation and be a valuable compound to overcome TRAIL resistance in breast cancer cells.	eupatolide	44-54	TNF superfamily member 10	Homo sapiens	69-74	
19956887-13	2010	Taken together, these results indicate that eupatolide could augment TRAIL-induced apoptosis in human breast cancer cells by down-regulating c-FLIP expression through the inhibition of AKT phosphorylation and be a valuable compound to overcome TRAIL resistance in breast cancer cells.	eupatolide	44-54	TNF superfamily member 10	Homo sapiens	244-249	
19956887-0	2010	The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression.	eupatolide	26-36	TNF superfamily member 10	Homo sapiens	71-76	
19956887-4	2010	We show, for the first time, that eupatolide, the sesquiterpene lactone isolated from the medicinal plant Inula britannica, sensitizes human breast cancer cells to TRAIL-induced apoptosis.	eupatolide	34-44	TNF superfamily member 10	Homo sapiens	164-169