PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22829094-3	2011	AZD1480 at low doses (0.1-1 mu) potently inhibited STATs phosphorylation, but did not predictably result in antiproliferative effects, as it activated a negative-feedback loop causing phosphorylation of JAK2 and extracellular signal-regulated kinases 1 and 2 (ERK1/2), and increased IP-10, RANTES and interleukin (IL)-8 concentrations in the supernatants.	AZD 1480	0-7	mitogen-activated protein kinase 3	Homo sapiens	260-266	
22829094-4	2011	Inhibition of the ERK activity by mitogen-activated extracellular signal regulated kinase (MEK) inhibitors (UO126 and PD98059) enhanced the cytotoxic activity of AZD1480.	AZD 1480	162-169	mitogen-activated protein kinase 3	Homo sapiens	18-21