PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2877539-4 1986 The relaxant activity as well as the level of intracellular cyclic GMP were restored in GTN-tolerant vessels by dipyridamole (5 microM), an agent with phosphodiesterase inhibiting properties. Dipyridamole 112-124 5'-nucleotidase, cytosolic II Homo sapiens 67-70 21043622-8 1995 In contrast, dipyridamole significantly increased the cyclic GMP content of endothelial cells in a dose dependent manner (1-10 muM). Dipyridamole 13-25 5'-nucleotidase, cytosolic II Homo sapiens 61-64 21043622-10 1995 These data suggest that the protective effect of dipyridamole against oxygen stress is correlated with the increase in the cyclic GMP content of the endothelial cells. Dipyridamole 49-61 5'-nucleotidase, cytosolic II Homo sapiens 130-133 11454657-4 2001 Phosphodiesterase inhibitors such as theophylline, pentoxyfylline, vinpocetine, dipyridamole and zaprinast, which increased the guanosine-3",5"-cyclic monophosphate (cyclic GMP) level, and dibutyryl cyclic GMP attenuated the H(2)O(2)-induced injury in astrocytes. Dipyridamole 80-92 5'-nucleotidase, cytosolic II Homo sapiens 173-176 11454657-4 2001 Phosphodiesterase inhibitors such as theophylline, pentoxyfylline, vinpocetine, dipyridamole and zaprinast, which increased the guanosine-3",5"-cyclic monophosphate (cyclic GMP) level, and dibutyryl cyclic GMP attenuated the H(2)O(2)-induced injury in astrocytes. Dipyridamole 80-92 5'-nucleotidase, cytosolic II Homo sapiens 206-209 11454657-6 2001 The cyclic GMP-dependent protein kinase inhibitor KT5823 blocked the protective effects of ibudilast and dipyridamole on the H(2)O(2)-induced decrease in cell viability, while the cyclic AMP-dependent protein kinase inhibitor KT5720, the cyclic AMP antagonist Rp-cyclic AMPS, the mitogen-activated protein/extracellular signal-regulated kinase inhibitor PD98059 and the leukotriene D(4) antagonist LY 171883 did not. Dipyridamole 105-117 5'-nucleotidase, cytosolic II Homo sapiens 11-14