PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25399587-2	2014	Glutaredoxin-1 (Glrx) is a cytosolic enzyme which enzymatically catalyses the reduction in S-glutathionylation, conferring reversible signalling function to proteins with redox-sensitive thiols.	Sulfhydryl Compounds	187-193	glutaredoxin	Mus musculus	0-14	
30682073-3	2019	Glutaredoxin-1 is a small cytosolic thioltransferase that controls a reversible protein thiol modification, S-glutationylation (protein-GSH adducts), thereby regulating redox signaling.	Sulfhydryl Compounds	36-41	glutaredoxin	Mus musculus	0-14	
27035878-2	2016	The oxidoreductase glutaredoxin-1 (Glrx1) under physiological conditions catalyzes deglutathionylation and restores the protein thiol group.	Sulfhydryl Compounds	128-133	glutaredoxin	Mus musculus	19-33	
27035878-2	2016	The oxidoreductase glutaredoxin-1 (Glrx1) under physiological conditions catalyzes deglutathionylation and restores the protein thiol group.	Sulfhydryl Compounds	128-133	glutaredoxin	Mus musculus	35-40	
25362663-1	2014	Glutaredoxin 2 (Grx2) is an isozyme of glutaredoxin1 (thioltransferase) present in the mitochondria and nucleus with disulfide reductase and peroxidase activities, and it controls thiol/disulfide balance in cells.	Sulfhydryl Compounds	54-59	glutaredoxin	Mus musculus	39-52	
27027965-2	2016	The oxidoreductase glutaredoxin-1 (Glrx1), under physiological conditions, catalyzes deglutathionylation and restores the protein thiol group.	Sulfhydryl Compounds	130-135	glutaredoxin	Mus musculus	35-40	
25399587-2	2014	Glutaredoxin-1 (Glrx) is a cytosolic enzyme which enzymatically catalyses the reduction in S-glutathionylation, conferring reversible signalling function to proteins with redox-sensitive thiols.	Sulfhydryl Compounds	187-193	glutaredoxin	Mus musculus	16-20	
15132975-5	2004	Oxidation of critical thiol groups by MPTP disrupts mitochondrial complex I, and up-regulation of glutaredoxin (a thiol disulfide oxidoreductase) is essential for recovery of complex I.	Sulfhydryl Compounds	22-27	glutaredoxin	Mus musculus	98-110	
20538586-0	2010	Postischemic deactivation of cardiac aldose reductase: role of glutathione S-transferase P and glutaredoxin in regeneration of reduced thiols from sulfenic acids.	Sulfhydryl Compounds	135-141	glutaredoxin	Mus musculus	95-107	
19664619-1	2009	We investigated if the absence of glutaredoxin1, a critical protein thiol repair enzyme, increases lens susceptibility to oxidative stress caused by in vivo exposure to ultraviolet radiation type B (UVR-B).	Sulfhydryl Compounds	68-73	glutaredoxin	Mus musculus	34-47	
24494201-7	2014	Neither metabolic stress nor UA supplementation altered mRNA or protein levels of glutaredoxin-1, the principal enzyme responsible for the reduction of mixed disulfides between glutathione and protein thiols in these cells.	Sulfhydryl Compounds	201-207	glutaredoxin	Mus musculus	82-96	
22523530-2	2012	Redox molecules thioredoxin (Trx) and glutaredoxin (Grx) superfamilies actively maintain intracellular thiol-redox homeostasis by scavenging reactive oxygen species.	Sulfhydryl Compounds	103-108	glutaredoxin	Mus musculus	38-50	
22523530-2	2012	Redox molecules thioredoxin (Trx) and glutaredoxin (Grx) superfamilies actively maintain intracellular thiol-redox homeostasis by scavenging reactive oxygen species.	Sulfhydryl Compounds	103-108	glutaredoxin	Mus musculus	52-55	
18586881-8	2008	TTase(-/-) LECs had significantly lower levels of glutathione (GSH) and protein thiols with extensive elevation of glutathionylated proteins, and they exhibited less resistance to oxidative stress than did TTase(+/+) cells.	Sulfhydryl Compounds	80-86	glutaredoxin	Mus musculus	0-5	
10469622-8	1999	Induction of thioredoxin, thioredoxin reductase and glutaredoxin activities by TPA and calcium ionophores may play a general role in the epigenetic mechanism of tumor promotion via thiol redox control mechanisms.	Sulfhydryl Compounds	181-186	glutaredoxin	Mus musculus	52-64	
12962915-2	2003	Glutaredoxin, a protein disulfide oxido-reductase mediates recovery of complex I by regenerating protein thiols utilizing reducing equivalents of glutathione.	Sulfhydryl Compounds	105-111	glutaredoxin	Mus musculus	0-12	
12594173-6	2003	Maintenance and restoration of protein thiol homeostasis by glutaredoxin may be important factors in preventing complex I dysfunction.	Sulfhydryl Compounds	39-44	glutaredoxin	Mus musculus	60-72	
35145079-2	2022	We report that in chow-fed, reproductively senescent female mice but not in age-matched male mice, deficiency in the thiol transferase glutaredoxin 1 (Grx1) promotes dysregulated macrophage phenotypes as well as rapid weight gain and atherogenesis.	Sulfhydryl Compounds	117-122	glutaredoxin	Mus musculus	135-149	
35145079-2	2022	We report that in chow-fed, reproductively senescent female mice but not in age-matched male mice, deficiency in the thiol transferase glutaredoxin 1 (Grx1) promotes dysregulated macrophage phenotypes as well as rapid weight gain and atherogenesis.	Sulfhydryl Compounds	117-122	glutaredoxin	Mus musculus	151-155