PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21428695-6 2011 Membrane-bound MGST1 is activated through the thiol modification in oxidative conditions. Sulfhydryl Compounds 46-51 microsomal glutathione S-transferase 1 Homo sapiens 15-20 21415529-1 2011 Membrane-bound glutathione transferases (MGST1) distributed mostly in liver microsomal and mitochondrial membranes are activated by the thiol modification. Sulfhydryl Compounds 136-141 microsomal glutathione S-transferase 1 Homo sapiens 41-46 21415529-4 2011 Although MGST1 was activated by the thiol alkylation with N-ethylmaleimide (NEM), the activation was suppressed in the presence of anionic phospholipids as clearly observed in the presence of CL. Sulfhydryl Compounds 36-41 microsomal glutathione S-transferase 1 Homo sapiens 9-14 16386761-5 2006 In addition, the MGST1 activity increased by nitric oxide (NO) donors such as S-nitrosoglutathione, S-nitrosocysteine or the non-thiol NO donor 1-hydroxy-2-oxo-3 (3-aminopropyl)-3-isopropyl was restored by the DTT treatment. Sulfhydryl Compounds 129-134 microsomal glutathione S-transferase 1 Homo sapiens 17-22 11258959-1 2001 An important aspect of the catalytic mechanism of microsomal glutathione transferase (MGST1) is the activation of the thiol of bound glutathione (GSH). Sulfhydryl Compounds 118-123 microsomal glutathione S-transferase 1 Homo sapiens 86-91 21415529-7 2011 These results indicate that reactivity (stability) of the thiol in MGST1 is affected by surrounding lipids, namely CL which prevents MGST1 activation by thiol modification. Sulfhydryl Compounds 58-63 microsomal glutathione S-transferase 1 Homo sapiens 67-72 21415529-7 2011 These results indicate that reactivity (stability) of the thiol in MGST1 is affected by surrounding lipids, namely CL which prevents MGST1 activation by thiol modification. Sulfhydryl Compounds 58-63 microsomal glutathione S-transferase 1 Homo sapiens 133-138 21415529-7 2011 These results indicate that reactivity (stability) of the thiol in MGST1 is affected by surrounding lipids, namely CL which prevents MGST1 activation by thiol modification. Sulfhydryl Compounds 153-158 microsomal glutathione S-transferase 1 Homo sapiens 67-72 21415529-7 2011 These results indicate that reactivity (stability) of the thiol in MGST1 is affected by surrounding lipids, namely CL which prevents MGST1 activation by thiol modification. Sulfhydryl Compounds 153-158 microsomal glutathione S-transferase 1 Homo sapiens 133-138 19348782-11 2009 In addition, the activity could be increased by thiol reagents (a hallmark of MGST1). Sulfhydryl Compounds 48-53 microsomal glutathione S-transferase 1 Homo sapiens 78-83