PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18287248-3 2008 In this report, we examined whether this flavone affects other cellular responses activated by TNF. flavone 41-48 tumor necrosis factor Homo sapiens 95-98 21907578-1 2011 It has been previously shown that some flavonoids inhibit NF-kappaB; however, the structure-activity relationships between chalcone, flavanone, flavone, and isoflavone derivatives and their TNFalpha induced NF-kappaB inhibitory effects on HCT116 human colon cancer cells have not yet been reported. flavone 144-151 tumor necrosis factor Homo sapiens 190-198 21040737-5 2011 Furthermore, apigenin, kaempferol, chrysin, and flavone significantly inhibited HG plus TNFalpha-induced LOX-1 expression. flavone 48-55 tumor necrosis factor Homo sapiens 88-96 18287248-7 2008 It is noteworthy that this flavone also suppressed TNF-induced activation of Akt, a cell survival kinase, and expression of various antiapoptotic proteins, such as IAP-1, IAP-2, XIAP, Bcl-2, Bcl-xL, and TRAF-1. flavone 27-34 tumor necrosis factor Homo sapiens 51-54