PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11861509-7 2002 Our findings demonstrate that the requirement for ERK1/2 activation as a regulator of progesterone synthesis in hGL cells is stimulus dependent, and that the MEK inhibitor-sensitive step is distal to cAMP generation, but proximal to the conversion of cholesterol to pregnenolone. Progesterone 86-98 LLGL scribble cell polarity complex component 2 Homo sapiens 112-115 34265413-6 2021 Using the primary culture of human granulosa-lutein (hGL) cells obtained from patients undergoing in vitro fertilization as a cell model, we show that treatment with BMP-9 downregulates steroidogenic acute regulatory protein (StAR) expression and suppresses progesterone (P4) production. Progesterone 258-270 LLGL scribble cell polarity complex component 2 Homo sapiens 53-56 35098302-5 2022 We found that IL-6 trans-signaling by the combined addition of IL-6 and soluble IL-6 receptor (sIL-6Ralpha) induced StAR expression and progesterone production in hGL cells. Progesterone 136-148 LLGL scribble cell polarity complex component 2 Homo sapiens 163-166 28867214-5 2018 Our results showed that LiCl significantly down-regulated the steroidogenic acute regulatory protein (StAR) expression and subsequent progesterone production in hGL cells. Progesterone 134-146 LLGL scribble cell polarity complex component 2 Homo sapiens 161-164