PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21819971-4 2011 Per2 and Clock siRNA treatment increased and unchanged, respectively, progesterone production in FSH-treated granulosa cells. Progesterone 70-82 clock circadian regulator Homo sapiens 9-14 30518737-4 2019 Knockdown of Clock gene by siRNA resulted in a significant reduction of estradiol production by inhibiting P450arom expression, while it induced a significant increase of progesterone production by upregulating 3betaHSD in KGN cells treated with forskolin. Progesterone 171-183 clock circadian regulator Homo sapiens 13-18 30518737-6 2019 Thus, the expression levels of Clock, being upregulated by forskolin and BMP-7, were functionally linked to estradiol production and progesterone suppression by human granulosa cells. Progesterone 133-145 clock circadian regulator Homo sapiens 31-36