PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31325580-0	2019	Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampus.	Progesterone	0-12	brain-derived neurotrophic factor	Rattus norvegicus	76-80	
31325580-11	2019	Our findings suggest that post-traumatic anti-epileptogenesis property of a high dose of progesterone partly occurs through the manipulation of BDNF-TrkB axis along with control of cell survival pathways.	Progesterone	89-101	brain-derived neurotrophic factor	Rattus norvegicus	144-148	
23154302-0	2013	Combination treatment with progesterone and vitamin D hormone is more effective than monotherapy in ischemic stroke: the role of BDNF/TrkB/Erk1/2 signaling in neuroprotection.	Progesterone	27-39	brain-derived neurotrophic factor	Rattus norvegicus	129-133	
26746666-3	2016	Rats underwent permanent middle cerebral artery occlusion (pMCAO) and then received intraperitoneal injections of progesterone (15 mg/kg) or vehicle at 1 h followed by subcutaneous injections at 6, 24, and 48 h. We examined VEGF and BDNF expression by Western blotting and/or immunostaining and microvessel density by lectin immunostaining.	Progesterone	114-126	brain-derived neurotrophic factor	Rattus norvegicus	233-237	
26746666-10	2016	Our data suggest that the enhancement of endogenous BDNF and subsequent neurogenesis could partially underlie the neuroprotective effects of progesterone.	Progesterone	141-153	brain-derived neurotrophic factor	Rattus norvegicus	52-56	
10536257-1	1999	Quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA) were used to examine the effects of acute estrogen and progesterone replacement on relative levels of brain-derived neurotrophic factor (BDNF) mRNA and protein in different regions of the adult rat brain.	Progesterone	171-183	brain-derived neurotrophic factor	Rattus norvegicus	218-251	
19175406-0	2009	Progesterone reverses 17beta-estradiol-mediated neuroprotection and BDNF induction in cultured hippocampal slices.	Progesterone	0-12	brain-derived neurotrophic factor	Rattus norvegicus	68-72	
18752305-1	2009	Several growth factors, such as vascular endothelial growth factor, brain-derived neurotrophic factor, and insulin-like growth factor-I are involved in the actions of progesterone in the central nervous system.	Progesterone	167-179	brain-derived neurotrophic factor	Rattus norvegicus	68-135	
18219447-0	2008	Progesterone pretreatment enhances serotonin-stimulated BDNF gene expression in rat c6 glioma cells through production of 5alpha-reduced neurosteroids.	Progesterone	0-12	brain-derived neurotrophic factor	Rattus norvegicus	56-60	
18219447-5	2008	Progesterone pretreatment enhanced the stimulatory action of serotonin on BDNF gene expression, and the enhancement of serotonin action observed in the cells pretreated with progesterone was almost completely abolished by finasteride, an inhibitor of the enzyme involved in the production of 5alpha-reduced neurosteroids.	Progesterone	0-12	brain-derived neurotrophic factor	Rattus norvegicus	74-78	
16085296-11	2005	BDNF levels in the hippocampus were increased by estrogen-priming, but reduced by progesterone administration.	Progesterone	82-94	brain-derived neurotrophic factor	Rattus norvegicus	0-4