PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17038555-5	2007	TNF-alpha treatment (1 nM for 48 h) decreased the basal production of cortisol, androstenedione, dehydroepiandrosterone sulfate (DHEAS), and aldosterone (14, 18, 35, and 52%, respectively), and the 8-bromo-cAMP-induced production of cortisol, androstenedione, dehydroepiandrosterone (DHEA), and DHEAS (44, 66, 58, and 48%, respectively).	Dehydroepiandrosterone Sulfate	97-127	tumor necrosis factor	Homo sapiens	0-9	
19902100-4	2009	At the stage of dendritic cell maturation, the effect of dehydroepiandrosterone sulfate manifested in a 4-fold increase in tumor necrosis factor-alpha production.	Dehydroepiandrosterone Sulfate	57-87	tumor necrosis factor	Homo sapiens	123-150	
15194576-2	2004	Adrenal androgens such as androstenedione (ASD) and dehydroepiandrosterone (DHEA) sulphate are low, which partly depends on the influence of TNF in chronic inflammatory diseases.	Dehydroepiandrosterone Sulfate	52-90	tumor necrosis factor	Homo sapiens	141-144	
14651593-7	2003	There was a significant inverse correlation between DHEA-S and IL-6, TNF-alpha, and CRP concentrations.	Dehydroepiandrosterone Sulfate	52-58	tumor necrosis factor	Homo sapiens	69-78	
11888843-7	2002	A multiple linear regression analysis revealed that elevated serum levels of TNF were associated with a high ratio of serum levels of DHEA/ASD in all groups (for IL-6 in patients with an acute inflammatory stressful disease state only), and, similarly, elevated serum levels of TNF were associated with a high ratio of serum levels of DHEAS/DHEA only in IBD (for IL-6 only in healthy subjects).	Dehydroepiandrosterone Sulfate	335-340	tumor necrosis factor	Homo sapiens	77-80	
11592593-7	2001	Levels of ACTH and DHEAS in relation to serum IL-6 or TNF were higher in Co as compared to the cholestatic subgroup without tumours, whereas serum cortisol in relation to these cytokines was similar.	Dehydroepiandrosterone Sulfate	19-24	tumor necrosis factor	Homo sapiens	54-57	
10929062-1	2000	This work examines the correlation between serum levels of oestrogen, progesterone and dehydroepiandrosterone sulphate (DHEA-S) and the number of human peripheral blood cells actively secreting interleukin (IL)-2, IL-4, IL-6, IL-10, tumour necrosis factor-alpha (TNF-alpha) or interferon-gamma (IFN-gamma) in vivo.	Dehydroepiandrosterone Sulfate	87-118	tumor necrosis factor	Homo sapiens	263-272	
8901021-1	1996	We investigated the effect of two neurosteroids, pregnenolone and dehydroepiandrosterone sulfate on lipopolysaccharide-induced tumor necrosis factor (TNF) production in vivo and in vitro.	Dehydroepiandrosterone Sulfate	66-96	tumor necrosis factor	Homo sapiens	127-148	
8901021-1	1996	We investigated the effect of two neurosteroids, pregnenolone and dehydroepiandrosterone sulfate on lipopolysaccharide-induced tumor necrosis factor (TNF) production in vivo and in vitro.	Dehydroepiandrosterone Sulfate	66-96	tumor necrosis factor	Homo sapiens	150-153	
8901021-8	1996	Dehydroepiandrosterone sulfate and pregnenolone (10(-6)-10(-4) M) inhibited TNF production in vitro by lipopolysaccharide-stimulated human peripheral blood mononuclear cells or by the human THP-1 cell line, suggesting that this action might also be relevant in humans.	Dehydroepiandrosterone Sulfate	0-30	tumor necrosis factor	Homo sapiens	76-79	
8901021-11	1996	(2) The inhibitory effect of dehydroepiandrosterone sulfate and pregnenolone on TNF production was not reversed by the glucocorticoid receptor antagonist, mifepristone (RU38486).	Dehydroepiandrosterone Sulfate	29-59	tumor necrosis factor	Homo sapiens	80-83	
15934093-0	2005	Tumor necrosis factor inhibits conversion of dehydroepiandrosterone sulfate (DHEAS) to DHEA in rheumatoid arthritis synovial cells: a prerequisite for local androgen deficiency.	Dehydroepiandrosterone Sulfate	45-75	tumor necrosis factor	Homo sapiens	0-21	
15934093-0	2005	Tumor necrosis factor inhibits conversion of dehydroepiandrosterone sulfate (DHEAS) to DHEA in rheumatoid arthritis synovial cells: a prerequisite for local androgen deficiency.	Dehydroepiandrosterone Sulfate	77-82	tumor necrosis factor	Homo sapiens	0-21	
15934093-9	2005	Neutralization of TNF largely up-regulated the conversion of DHEAS to DHEA in RA, but not in OA.	Dehydroepiandrosterone Sulfate	61-66	tumor necrosis factor	Homo sapiens	18-21	
15934093-11	2005	CONCLUSION: These data indicate that TNF inhibits the conversion of DHEAS to DHEA in RA synovial cells.	Dehydroepiandrosterone Sulfate	68-73	tumor necrosis factor	Homo sapiens	37-40	
9218249-1	1996	We previously reported that neurosteroids, including dehydroepiandrosterone sulfate (DHEAS), inhibit the production of TNF in vitro and in vivo.	Dehydroepiandrosterone Sulfate	53-83	tumor necrosis factor	Homo sapiens	119-122